Calorie Restriction With Leucine Supplementation
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Obesity Weight Loss, Osteoporosis, Orthopedic, Women's Studies |
| Therapuetic Areas: | Endocrinology, Rheumatology, Orthopedics / Podiatry, Reproductive |
| Healthy: | No |
| Age Range: | 50 - 65 |
| Updated: | 7/21/2016 |
| Start Date: | September 2012 |
| End Date: | December 2016 |
Calorie Restriction With Leucine Supplementation in Postmenopausal Women
The purpose of this study is to determine whether consuming additional leucine during
calorie restriction induced weight loss has beneficial or harmful effects on multi-organ
(liver, muscle, adipose tissue) insulin sensitivity, colonocyte proliferation rates, the gut
microbiome, muscle mass and function, and bone mineral density in obese, postmenopausal
women.
calorie restriction induced weight loss has beneficial or harmful effects on multi-organ
(liver, muscle, adipose tissue) insulin sensitivity, colonocyte proliferation rates, the gut
microbiome, muscle mass and function, and bone mineral density in obese, postmenopausal
women.
Inclusion Criteria:
- Obese with body mass index (BMI) between 30 and 40 kg/m2
- Postmenopausal
- Sedentary (i.e., less than 1.5 hours of exercise per week)
Exclusion Criteria:
- Individuals with diabetes and/or uncontrolled hypertension
- Individuals with hepatitis B and/or C
- Individuals who smoke
- Individuals with an allergy to whey protein
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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