Optimal Timing of Cord Clamping in Preterm Pregnancy Following Vaginal or Cesarean Delivery
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 2/7/2015 |
| Start Date: | December 2012 |
| End Date: | December 2014 |
| Contact: | James N Martin, JR, MD |
| Email: | jnmartin@umc.edu |
| Phone: | 601-984-5358 |
Timing of Umbilical Cord Clamping After Vaginal or Cesarean Preterm Birth
This is an experimental research study for pregnant women between 23 and 37 weeks age of
gestation who will be having a baby sooner than term. This study is to learn if waiting 20,
40, or 60 seconds to clamp the umbilical cord after baby delivers will improve his/her
outcome and overall health. Benefit to the baby may come by increasing the amount of blood
in the baby's body, reducing the need for possible transfusion later, and possible
prevention of other complications caused by too little blood in the baby. Possible
reduction of cerebral palsy may be realized by a longer interval for cord clamping.
gestation who will be having a baby sooner than term. This study is to learn if waiting 20,
40, or 60 seconds to clamp the umbilical cord after baby delivers will improve his/her
outcome and overall health. Benefit to the baby may come by increasing the amount of blood
in the baby's body, reducing the need for possible transfusion later, and possible
prevention of other complications caused by too little blood in the baby. Possible
reduction of cerebral palsy may be realized by a longer interval for cord clamping.
Intention is to enroll every preterm delivery into this trial containing six groups of
patients, vaginal or cesarean delivery with clamping of the cord at 20, 40 or 60 seconds.
Expectation is 1500 deliveries over 2 year period of time. Randomization upon entry to L&D
unit. Removal from study if resuscitation deemed urgent by newborn staff. Strong effort to
keep newborn warm using appropriate measures. Evaluation to determine if there are
differences in transfusion, anemia, time to onset of spontaneous respiration, occurence of
IVH or CP.
patients, vaginal or cesarean delivery with clamping of the cord at 20, 40 or 60 seconds.
Expectation is 1500 deliveries over 2 year period of time. Randomization upon entry to L&D
unit. Removal from study if resuscitation deemed urgent by newborn staff. Strong effort to
keep newborn warm using appropriate measures. Evaluation to determine if there are
differences in transfusion, anemia, time to onset of spontaneous respiration, occurence of
IVH or CP.
Inclusion Criteria:
18 years old singleton gestation Between 23-37 weeks gestation Able to understand and sign
informed consent
Exclusion Criteria:
multiple gestation/ known intrauterine fetal death unable to sign consent
We found this trial at
1
site
Jackson, Mississippi 39216
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