Direct Peritoneal Resuscitation Effects in the Damage Control Patient
| Status: | Completed |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 10/14/2017 |
| Start Date: | January 2012 |
| End Date: | June 2016 |
The purpose of this study is to find if direct peritoneal resuscitation helps blood flow
through important organs in a person's body after they have had a traumatic injury with
massive blood loss. Sometimes after severe injuries requiring operation, surgeons cannot
close the muscles and skin of a patient's belly, because of swelling. This study will also
try to find if direct peritoneal resuscitation decreases tissue swelling and allows for
quicker closure of of a patient's belly.
through important organs in a person's body after they have had a traumatic injury with
massive blood loss. Sometimes after severe injuries requiring operation, surgeons cannot
close the muscles and skin of a patient's belly, because of swelling. This study will also
try to find if direct peritoneal resuscitation decreases tissue swelling and allows for
quicker closure of of a patient's belly.
Standard methods of controlling bleeding and increasing blood flow to vital organs will be
used. These methods include giving blood and fluids and surgically repairing the vessels that
are causing the bleeding which are standard ways physicians treat injuries with massive blood
loss. A drain (a small plastic tube) will be placed inside the belly.
Subjects will randomly (like flipping a coin) be placed into a group of patients who either
get a sugar solution dripped into the belly after surgery or do not get this treatment. The
drain will be used to drip a high glucose solution into the abdomen in patients be part of
that group. The fluid will continue to be dripped into the belly until it is possible to
close the skin and underlying layers.
used. These methods include giving blood and fluids and surgically repairing the vessels that
are causing the bleeding which are standard ways physicians treat injuries with massive blood
loss. A drain (a small plastic tube) will be placed inside the belly.
Subjects will randomly (like flipping a coin) be placed into a group of patients who either
get a sugar solution dripped into the belly after surgery or do not get this treatment. The
drain will be used to drip a high glucose solution into the abdomen in patients be part of
that group. The fluid will continue to be dripped into the belly until it is possible to
close the skin and underlying layers.
Inclusion Criteria:
- All trauma patients age 18 years or greater with massive blood loss
- Patients requiring a damage control procedure
- Traumatic injury within the last 24 hours
Exclusion Criteria:
- Patients who are pregnant
- Less than 18 years of age
- Known chronic renal disease
- Moribund
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