Functional Brain Imaging of Pain Phenotype and Genotype
| Status: | Completed |
|---|---|
| Conditions: | Chronic Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 5/4/2018 |
| Start Date: | January 2013 |
| End Date: | March 2016 |
Brain Imaging of Pain Phenotype and Genotype With Novel Scanning Techniques
This study has two purposes: first, to locate and identify the "brain activation" (the areas
of the brain) which respond to pain; and second, to look at how brain activation is
influenced by a person's genetics (the traits they inherited from their parents). A Magnetic
Resonance Imaging (MRI) scanner will be used to gather pictures of the brain (similar to an
x-ray, but based on different scientific principles) that will be used to determine which
areas are active. The hypothesis is that the variation in brain activity between people can
be partially explained by genetic differences. This study consists of an two pain tasks
applied during a one time visit to the MRI suite. There are no followup visits.
of the brain) which respond to pain; and second, to look at how brain activation is
influenced by a person's genetics (the traits they inherited from their parents). A Magnetic
Resonance Imaging (MRI) scanner will be used to gather pictures of the brain (similar to an
x-ray, but based on different scientific principles) that will be used to determine which
areas are active. The hypothesis is that the variation in brain activity between people can
be partially explained by genetic differences. This study consists of an two pain tasks
applied during a one time visit to the MRI suite. There are no followup visits.
Inclusion Criteria:
- Age 18 to 50
- Right-handed
- Male or female
- Healthy individuals not taking any medication.
Exclusion Criteria:
- Pregnancy
- Diagnosed with any treated or untreated medical or neurological conditions
- Using any prescription drugs, including antidepressants, pain medications, sedative
medications, blood pressure medications, seizure medications, or antipsychotics. Oral
contraceptives are permitted
- Using any over-the-counter medications including aspirin, Tylenol, or herbal
supplements
- Using any illicit substances
- Contraindications to magnetic resonance imaging.
We found this trial at
1
site
4200 Fifth Ave
Pittsburgh, Pennsylvania 15260
Pittsburgh, Pennsylvania 15260
(412) 624-4141
Principal Investigator: James W Ibinson, MD, PhD
Phone: 412-383-5911
University of Pittsburgh The University of Pittsburgh is a state-related research university, founded as the...
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