Comparison of Standard Versus Low Bicarbonate Hemodialysis



Status:Completed
Conditions:Renal Impairment / Chronic Kidney Disease
Therapuetic Areas:Nephrology / Urology
Healthy:No
Age Range:19 - Any
Updated:5/27/2013
Start Date:January 2013
End Date:June 2013
Contact:William Paredes
Email:bill.paredes@einstein.yu.edu
Phone:718-430-3088

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Intradialytic Acid-base Changes and Organic Anion Production With Standard Versus Low Bicarbonate Hemodialysis


This study will compare acid-base changes during hemodialysis treatments with a standard
dialysis bath versus a lower bicarbonate dialysis bath, and aims to define the factors that
limit equilibration of the bicarbonate concentration in a patient's blood with that in the
dialysate.


Inclusion Criteria:

- Receiving chronic thrice-weekly conventional hemodialysis for at least 3 months

- Age > 18 years

Exclusion Criteria:

- Use of oral alkali within the previous month

- Hospitalization within the previous month

- Inability to provide written informed consent

- Pregnancy
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