The Role of Mid-Life Adiposity in Functional Brain Connectivity
| Status: | Terminated |
|---|---|
| Conditions: | Alzheimer Disease, Healthy Studies |
| Therapuetic Areas: | Neurology, Other |
| Healthy: | No |
| Age Range: | 45 - 65 |
| Updated: | 4/21/2016 |
| Start Date: | December 2012 |
| End Date: | February 2016 |
The purpose of the study is to use functional MRI (fMRI) to measure brain connectivity in
middle-aged individuals with different levels of body fat. The ultimate goal of this
research is to develop an early diagnostic tool for Alzheimer's disease.
middle-aged individuals with different levels of body fat. The ultimate goal of this
research is to develop an early diagnostic tool for Alzheimer's disease.
Participants will have one visit for:
- Blood draw
- Body composition scan
- Cognitive screen
- Neurological exam
- MRI scan
The visit will take approximately 3 hours.
- Blood draw
- Body composition scan
- Cognitive screen
- Neurological exam
- MRI scan
The visit will take approximately 3 hours.
Inclusion Criteria:
- 45-65 years of age
- Normal memory
- Right-handed
- General good physical health
Exclusion Criteria:
- History of stroke or neurological disease
- Seizures or head injury with loss of consciousness within the last five years
- Ferrous (magnetic) or electronic implants (due to the magnet in the MRI scanner)
- Claustrophobia
More detailed inclusion/exclusion criteria must be met in order to qualify for the study.
The study coordinator will determine eligibility.
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