Developing an Intervention to Prevent Visceral Adipose Tissue Accumulation



Status:Recruiting
Conditions:Obesity Weight Loss, Women's Studies
Therapuetic Areas:Endocrinology, Reproductive
Healthy:No
Age Range:42 - 52
Updated:3/1/2014
Start Date:April 2012
Contact:Chiquia Hollings
Email:Chiquia_S_Hollings@rush.edu
Phone:3125632120

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Developing an Intervention to Prevent Visceral Adipose Tissue Accumulation in Premenopausal Women: WISHfit Phase 2

The aim of this study is to develop an intervention that will produce a sustained
improvement in physical activity and chronic stress as a means to slow the menopause-related
accumulation of visceral adipose tissue in mid-life women.


Inclusion Criteria:

- Resident of the Beverly or Morgan Park neighborhood of Chicago or contiguous
neighborhoods

- Female

- African American or Caucasian

- Age 42 to 52

- Intact uterus, at least one functioning ovary, at least one menstrual period in the
last 12 months prior to screening.

- Sufficient motivation level to make lifestyle changes, as determined by WISHFIT
staff.

Exclusion Criteria:

- Hysterectomy

- Physical activity > 90 min per week

- Metabolic conditions or use of medications that affect weight of visceral adipose
tissue (diabetes, acquired immune deficiency syndrome, weight > 300 lbs)

- Presence or history of major psychiatric comorbidity (i.e. dementia, schizophrenia,
bipolar disorder, alcohol/drug addiction) in the last 6 months

- History of inpatient mental health treatment

- Currently prescribed antipsychotic medication

- History of hallucinations or bizarre thoughts

- Current pregnancy

- Has been told by a physician that it is unsafe to engage in physical activity

- An illness expected to limit functional status or life expectancy, including: heart
failure, recent heart attack, liver cirrhosis, kidney failure, oncologic conditions,
history or heart surgery, angioplasty or artery stenting.
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