Cytogenetic Study of Ocular Melanoma



Status:Recruiting
Conditions:Skin Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:9/14/2017
Start Date:January 8, 2005
End Date:August 31, 2021
Contact:Tara A McCannel, MD, PhD
Email:tmccannel@jsei.ucla.edu
Phone:310-206-7484

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Trial Summary
Trial Overview
Inclusion Criteria

Molecular and Cytogenetic Studies of Ocular Melanoma

Patients who are diagnosed with choroidal melanoma and undergo I-125 plaque or enucleation
surgery consent to participate in the study. A tumor sample taken during surgery is studied
in the lab for genetic features. These features and features of subjects' clinical course are
recorded. Analysis of the data may identify genetic features that are indicative of
prognostic factors including risk of metastasis.

The Jules Stein Eye Institute Ocular Melanoma Research Group is conducting cytogenetic
studies of choroidal melanoma to improve the screening of biopsy samples of choroidal
melanoma through cytogenetic analysis. Our goal is to identify molecular probes that
specifically target regions of chromosomes that undergo changes characteristic of metastatic
choroidal melanoma.

Inclusion Criteria:

1. Patient with diagnosis of ocular melanoma

2. Patient with local treatment plan for ocular melanoma- plaque brachytherapy or
enucleation

3. Patient 18 years of age or older

4. Archival enucleation specimens with diagnosis of ocular melanoma

Exclusion Criteria:

1. Patient who refuses local melanoma treatment

2. Patient who refuses to participate in this study
We found this trial at
1
site
Jules Stein Eye Institute
100 Stein Plaza
Los Angeles, California 90095
Phone: 310-794-9962
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Los Angeles, CA
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