Echo-guided Hemodynamic Management Strategy in Elderly Patients Undergoing Noncardiac Surgery



Status:Completed
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:70 - Any
Updated:8/30/2018
Start Date:September 2014
End Date:August 27, 2018

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Echocardiography-guided Hemodynamic (EGHEM) Management Strategy to Improve Clinical Outcomes for Elderly Patients With Left Ventricular Diastolic Dysfunction (LVDD) Undergoing Non-cardiac Surgery

Elderly patients are the fastest growing surgical population and present with increased risk
of postoperative cardiac problems, especially congestive heart failure. Diastolic dysfunction
is common in the elderly population and increases the risk of major adverse cardiac events
after surgery. This project will use dynamic measurements of diastolic filling pressures by
echocardiography for goal-directed fluid and drug management during surgery to determine
whether this reduces serious cardiac events related to diastolic dysfunction after surgery in
this high-risk population.


Inclusion Criteria:

- Age 70 years and older

- Echocardiographic Evidence of Grade I, II or III LVDD on Preoperative Transthoracic
Echocardiography (TTE) examination

- Undergoing Vascular Surgery including but not limited to : Lower extremity bypass,Open
abdominal aortic aneurysm repair

Exclusion Criteria:

- Patients with expected hospital stay < 24 hours

- Inability to undergo TEE and Transesophageal Echocardiography(TTE)

- Clinical evidence/suspicion of elevated Intercranial Pressure (ICP)

- Preoperative shock or systemic sepsis

- Emergency operation

- American Society of Anesthesiologists Status V

- Participation in another clinical trial

- General Anesthesia not planned for procedure
We found this trial at
1
site
Emile St
Omaha, Nebraska 68198
(402) 559-4000
Phone: 402-559-2849
Univ of Nebraska Med Ctr A vital enterprise in the nation’s heartland, the University of...
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