Study Evaluating 13 Valent Pneumococcal Conjugate Vaccine With Trivalent Inactivated Influenza Vaccine



Status:Completed
Conditions:Influenza
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:50 - 59
Updated:11/30/-0001
Start Date:September 2007
End Date:January 2014
Contact:Pfizer CT.gov Call Center
Phone:1-800-718-1021

Use our guide to learn which trials are right for you!

A Phase 3, Randomized, Double Blind Trial To Evaluate The Safety, Tolerability, And Immunogenicity Of A 13 Valent Pneumococcal Conjugate Vaccine (13vPnC) When Administered Concomitantly With Trivalent Inactivated Influenza Vaccine (TIV) In Healthy Adults 50-59 Years Of Age Who Are Naive To 23-Valent Pneumococcal Polysaccharide Vaccine And To Evaluate The Immune Response Of A Second Dose Of 13vPnC Administered 5 Years After Initial 13vPnC Vaccination


This study is to evaluate the safety, tolerability and immune response when 13-valent
pneumococcal conjugate vaccine (13vPnC) and the trivalent inactivated flu vaccine (TIV) are
given together to healthy adults aged 50-59 years who are naive to 23-valent pneumococcal
polysaccharide vaccine (23vPS), or when the vaccines are given 1 month apart. It will also
evaluate the immune response to 13vPnC once per year for 4 years and then to a second dose
of 13vPnC given 5 years after the first dose.


Inclusion Criteria:

- Male or female aged 50 to 59 years

- Determined by medical history, physical examination and clinical judgement to be
eligible for the study

- Able to complete electronic diary

- Available for the 5 year 9 month duration of the study

Exclusion Criteria:

- Previous vaccination with any licensed or experimental pneumococcal vaccine

- Allergic to egg proteins and chicken proteins

- History of Guillian-Barre syndrome

- Vaccination with TIV within 6 months before study start

- Vaccination with diphtheria-containing vaccine within 6 months of study start

- Serious chronic disorders including immunodeficiency or metastatic malignancy

- Known or suspected hypersensitivity to any vaccine or vaccine component
We found this trial at
18
sites
Houston, Texas 77030
1892
mi
from 98109
Houston, TX
Click here to add this to my saved trials
Akron, Ohio 44314
2041
mi
from 98109
Akron, OH
Click here to add this to my saved trials
Arvada, Colorado 80005
1010
mi
from 98109
Arvada, CO
Click here to add this to my saved trials
Asheville, North Carolina 28801
2187
mi
from 98109
Asheville, NC
Click here to add this to my saved trials
Atlantis, Florida 33462
2698
mi
from 98109
Atlantis, FL
Click here to add this to my saved trials
Baltimore, Maryland 21234
2328
mi
from 98109
Baltimore, MD
Click here to add this to my saved trials
Bloomingdale, Illinois 60108
1710
mi
from 98109
Bloomingdale, IL
Click here to add this to my saved trials
Boise, Idaho 83702
405
mi
from 98109
Boise, ID
Click here to add this to my saved trials
Bossier City, Louisiana 71111
1820
mi
from 98109
Bossier City, LA
Click here to add this to my saved trials
Bristol, Tennessee 37620
2168
mi
from 98109
Bristol, TN
Click here to add this to my saved trials
Cape Girardeau, Missouri 63703
1801
mi
from 98109
Cape Girardeau, MO
Click here to add this to my saved trials
Duluth, Minnesota 55805
1411
mi
from 98109
Duluth, MN
Click here to add this to my saved trials
Gilbert, Arizona 85234
1129
mi
from 98109
Gilbert, AZ
Click here to add this to my saved trials
Kalispell, Montana 59901
373
mi
from 98109
Kalispell, MT
Click here to add this to my saved trials
Los Angeles, California 90027
979
mi
from 98109
Los Angeles, CA
Click here to add this to my saved trials
Pittsburgh, Pennsylvania 15212
2131
mi
from 98109
Pittsburgh, PA
Click here to add this to my saved trials
Rochester, New York 14642
2154
mi
from 98109
Rochester, NY
Click here to add this to my saved trials
West Jordan, Utah 84088
706
mi
from 98109
West Jordan, UT
Click here to add this to my saved trials