A Study Of PF-00547659 In Patients With Moderate To Severe Ulcerative Colitis



Status:Active, not recruiting
Conditions:Colitis, Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 65
Updated:4/21/2016
Start Date:November 2012
End Date:January 2016

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A Double-blind, Randomized, Placebo-controlled, Parallel, Dose-ranging Study To Evaluate The Efficacy And Safety Of Pf-00547659 In Subjects With Moderate To Severe Ulcerative Colitis (Turandot)

To determine the dose or doses of PF-00547659 that will be the most effective to improve or
halt the disease symptoms in patients with moderate to severe ulcerative colitis.


Inclusion Criteria:

- Subjects with diagnosis of Ulcerative Colitis for 3 or more months.

- Ulcerative colitis must be active beyond the rectum.

- Must active Ulcerative Colitis with a Total Mayo Score of 6 to 12 points

Exclusion Criteria:

- Pregnant or breast feeding.

- Diagnosis of indeterminate colitis or Crohn's Disease

- Subjects with history of colonic or small bowel obstruction or resection.
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Chapel Hill, North Carolina 27599
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University of North Carolina at Chapel Hill Carolina’s vibrant people and programs attest to the...
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Lexington, Kentucky 40536
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Winter Park, Florida 32789
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Albany, New York 12208
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1 Medical Center Dr
Lebanon, New Hampshire 03756
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Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
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1400 NW 12th Ave
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University of Miami Hospital The University of Miami changed the face of modern health care...
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Poughkeepsie, New York 12601
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13400 E. Shea Blvd.
Scottsdale, Arizona 85259
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