A Study Of PF-00547659 In Patients With Moderate To Severe Ulcerative Colitis



Status:Active, not recruiting
Conditions:Colitis, Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 65
Updated:4/21/2016
Start Date:November 2012
End Date:January 2016

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A Double-blind, Randomized, Placebo-controlled, Parallel, Dose-ranging Study To Evaluate The Efficacy And Safety Of Pf-00547659 In Subjects With Moderate To Severe Ulcerative Colitis (Turandot)

To determine the dose or doses of PF-00547659 that will be the most effective to improve or
halt the disease symptoms in patients with moderate to severe ulcerative colitis.


Inclusion Criteria:

- Subjects with diagnosis of Ulcerative Colitis for 3 or more months.

- Ulcerative colitis must be active beyond the rectum.

- Must active Ulcerative Colitis with a Total Mayo Score of 6 to 12 points

Exclusion Criteria:

- Pregnant or breast feeding.

- Diagnosis of indeterminate colitis or Crohn's Disease

- Subjects with history of colonic or small bowel obstruction or resection.
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Chapel Hill, North Carolina 27599
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