Study to Evaluate the Effects of BMS-813160 on Protein Loss in the Urine of Subjects With Type 2 Diabetes and Diabetic Kidney Disease



Status:Completed
Conditions:Renal Impairment / Chronic Kidney Disease, Diabetes
Therapuetic Areas:Endocrinology, Nephrology / Urology
Healthy:No
Age Range:18 - 85
Updated:4/21/2016
Start Date:March 2013
End Date:June 2015

Use our guide to learn which trials are right for you!

A Double-Blind, Placebo-Controlled, Randomized, Two-stage, Parallel-Group, Adaptive Design Phase 2a Study to Evaluate the Effects of BMS-813160 in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease (DKD) Who Have Residual Macroalbuminuria Despite Treatment With an Inhibitor of the Renin-Angiotensin System

The purpose of this study is to determine whether BMS-813160 will reduce the amount of
protein loss in the urine of subjects with type 2 diabetes and diabetic kidney disease


For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com

Inclusion Criteria:

- Clinical diagnosis of type 2 diabetes mellitus with macroalbuminuria (UACR between
200 and 3500 mg/g)

- Background angiotensin converting enzyme inhibitor (ACEI) or angiotensin-receptor
blocker (ARB) therapy

Exclusion Criteria:

- Clinical diagnosis of type 1 diabetes

- Unstable cardiovascular, metabolic, or other chronic disease status

- Estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m2

- High risk of infection or immune compromise

- Clinically significant ECG conduction abnormalities

- Drugs with significant potential to affect BMS-813160 exposure
We found this trial at
38
sites
Northridge, California 91325
1981
mi
from 43215
Northridge, CA
Click here to add this to my saved trials
1648 Pierce Dr NE
Atlanta, Georgia 30322
(404) 727-5640
Emory University School of Medicine Emory University School of Medicine has 2,359 full- and part-time...
432
mi
from 43215
Atlanta, GA
Click here to add this to my saved trials
Durham, North Carolina 27710
(919) 684-8111
Duke University Younger than most other prestigious U.S. research universities, Duke University consistently ranks among...
352
mi
from 43215
Durham, NC
Click here to add this to my saved trials
1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
333
mi
from 43215
Nashville, TN
Click here to add this to my saved trials
Albany, New York 12206
513
mi
from 43215
Albany, NY
Click here to add this to my saved trials
Birmingham, Alabama 35294
492
mi
from 43215
Birmingham, AL
Click here to add this to my saved trials
Boone, North Carolina 28607
269
mi
from 43215
Boone, NC
Click here to add this to my saved trials
Burke, Virginia 22015
317
mi
from 43215
Burke, VA
Click here to add this to my saved trials
Charlotte, North Carolina 28204
348
mi
from 43215
Charlotte, NC
Click here to add this to my saved trials
Chesapeake, Virginia 23321
418
mi
from 43215
Chesapeake, VA
Click here to add this to my saved trials
1969 W Ogden Ave
Chicago, Illinois 60612
(312) 864-6000
John H. Stroger, Jr. Hospital of Cook County The Level 1 Trauma Center is one...
277
mi
from 43215
Chicago, IL
Click here to add this to my saved trials
410 W 10th Ave
Columbus, Ohio 43210
(614) 293-8652
The Ohio State University, Wexner Medical Center Located in Columbus, The Ohio State University Wexner...
1
mi
from 43215
Columbus, OH
Click here to add this to my saved trials
Cooper City, Florida 33024
973
mi
from 43215
Cooper City, FL
Click here to add this to my saved trials
Edinburg, Texas 78539
1286
mi
from 43215
Edinburg, TX
Click here to add this to my saved trials
Evergreen Park, Illinois 60805
272
mi
from 43215
Evergreen Park, IL
Click here to add this to my saved trials
Flushing, New York 11355
486
mi
from 43215
Flushing, NY
Click here to add this to my saved trials
Fort Sam Houston, Texas 78234
1135
mi
from 43215
Fort Sam Houston, TX
Click here to add this to my saved trials
986
mi
from 43215
Hialeah, FL
Click here to add this to my saved trials
Hodges, South Carolina 29646
404
mi
from 43215
Hodges, SC
Click here to add this to my saved trials
Los Angeles, California 90022
1968
mi
from 43215
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90095
(310) 825-4321
UCLA UCLA's primary purpose as a public research university is the creation, dissemination, preservation and...
1982
mi
from 43215
Los Angeles, CA
Click here to add this to my saved trials
Manassas, Virginia 20110
307
mi
from 43215
Manassas, VA
Click here to add this to my saved trials
Middleburg Heights, Ohio 44130
116
mi
from 43215
Middleburg Heights, OH
Click here to add this to my saved trials
Nashua, New Hampshire 03063
627
mi
from 43215
Nashua, NH
Click here to add this to my saved trials
North Hollywood, California 91606
1976
mi
from 43215
North Hollywood, CA
Click here to add this to my saved trials
684
mi
from 43215
Omaha, NE
Click here to add this to my saved trials
1020 Walnut St
Philadelphia, Pennsylvania 19107
(215) 955-6000
Thomas Jefferson University We are dedicated to the health sciences and committed to educating professionals,...
416
mi
from 43215
Philadelphia, PA
Click here to add this to my saved trials
Phoenix, Arizona 85012
1662
mi
from 43215
Phoenix, AZ
Click here to add this to my saved trials
Richmond, Virginia 23249
342
mi
from 43215
Richmond, VA
Click here to add this to my saved trials
Roswell, Georgia 30076
417
mi
from 43215
Roswell, GA
Click here to add this to my saved trials
Saint Louis, Missouri 63128
406
mi
from 43215
Saint Louis, MO
Click here to add this to my saved trials
1121
mi
from 43215
Schertz, TX
Click here to add this to my saved trials
Tampa, Florida 33614
826
mi
from 43215
Tampa, FL
Click here to add this to my saved trials
Trenton, New Jersey 08611
436
mi
from 43215
Trenton, NJ
Click here to add this to my saved trials
Walnut creek, California 94598
2083
mi
from 43215
Walnut creek, CA
Click here to add this to my saved trials
Washington, District of Columbia 20037
328
mi
from 43215
Washington,
Click here to add this to my saved trials
970
mi
from 43215
Winnipeg,
Click here to add this to my saved trials
Zanesville, Ohio 43701
53
mi
from 43215
Zanesville, OH
Click here to add this to my saved trials