The Effect of Aerobic Exercise on Cognitive Function and Sleep Quality in Individuals With Multiple Sclerosis
| Status: | Completed |
|---|---|
| Conditions: | Neurology, Multiple Sclerosis |
| Therapuetic Areas: | Neurology, Other |
| Healthy: | No |
| Age Range: | 21 - 80 |
| Updated: | 4/21/2016 |
| Start Date: | August 2012 |
| End Date: | December 2015 |
In addition to the typical motor and sensory impairments, individuals with multiple
sclerosis (MS) often experience cognitive dysfunction and sleep disturbances. Cognitive
impairment occurs in 40 % - 70% of patients with MS. In addition, sleep problems in
individuals with MS are very common, and approximately 50% of patients with MS have a
diagnosable sleep disorder. The research believes that aerobic exercise improve cognitive
function and improve sleep quality.
sclerosis (MS) often experience cognitive dysfunction and sleep disturbances. Cognitive
impairment occurs in 40 % - 70% of patients with MS. In addition, sleep problems in
individuals with MS are very common, and approximately 50% of patients with MS have a
diagnosable sleep disorder. The research believes that aerobic exercise improve cognitive
function and improve sleep quality.
Inclusion Criteria:
- diagnosis of relapsing remitting or secondary progressive MS
- score 3-7 on the EDSS
- score < 55 on the Symbol Digit Modalities Test
- score > 5 on the Pittsburgh Sleep Quality Index
Exclusion Criteria:
- history of alcohol/drug abuse or nervous system disorder other than MS
- severe physical, neurological, or sensory impairments that would interfere
significantly with testing
- developmental history of learning disability or attention-deficit/hyperactivity
disorder
- relapse and/or corticosteroid use within four weeks of assessment
- unable to give consent
- uncorrected vision loss that would interfere significantly with testing
- score less than 24 on MMSE
- Acute ischemic cardiovascular event or coronary artery bypass surgery less than 3
months ago
- Either unable to physically perform the exercise test using the recumbent stepper or
demonstrate absolute indications for terminating exercise that follows the American
College of Sports Medicine's (ACSM) guidelines
- Uncontrolled blood pressure with medication (BP > 190/110mmHg)
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