Music for Health Project
| Status: | Active, not recruiting |
|---|---|
| Conditions: | HIV / AIDS |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/26/2017 |
| Start Date: | June 2014 |
| End Date: | June 30, 2017 |
An Audio Music Self-Management Program to Improve ART Adherence in Rural GA
The overall goal of this project is to use technology to improve adherence to antiretroviral
therapy (ART)and increase access to ART adherence care for those HIV+ persons living in
rural areas. The LIVE Network audio music program mobile application (app) is innovative,
practical, portable, and could be rapidly scaled up to address the adherence self-management
needs of rural groups nationwide. If successful, the impact on HIV care will be immense and
could transform the delivery of HIV self-management and adherence education by overcoming
barriers of geographic isolation, transportation, stigma and confidentiality in this
vulnerable group.
therapy (ART)and increase access to ART adherence care for those HIV+ persons living in
rural areas. The LIVE Network audio music program mobile application (app) is innovative,
practical, portable, and could be rapidly scaled up to address the adherence self-management
needs of rural groups nationwide. If successful, the impact on HIV care will be immense and
could transform the delivery of HIV self-management and adherence education by overcoming
barriers of geographic isolation, transportation, stigma and confidentiality in this
vulnerable group.
The project has two primary aims and one exploratory aim. 1.0 Revise and adapt the Live
Network (LN) program and manual for rural persons living with HIV/AIDS (PLWHA) and develop
into a mobile application.
2.0 Conduct a randomized controlled trial to test the efficacy of the program. When compared
with an educational music control condition at 3, 6, and 9 months post-baseline, those
randomized to the LN will have: H1: Significantly higher mean antiretroviral therapy (ART)
adherence rates (measured by pill counts, self report).
H2: Significantly higher mean levels of ART drug levels in hair sample analyses.
H3: Significantly better clinical indicators: higher mean CD4 lymphocyte counts and
percents, a larger proportion achieving virologic suppression (proportion with HIV RNA PCR
<50 copies/ml), and smaller proportion with evidence of drug resistance, all as measured by
medical record review.
3.0 Explore: a) the effects of LN on symptoms and symptom management; b) the roles of
self-efficacy, outcome expectancies, and personal goal setting as mediators, and depression
and health literacy as moderators of adherence.
Network (LN) program and manual for rural persons living with HIV/AIDS (PLWHA) and develop
into a mobile application.
2.0 Conduct a randomized controlled trial to test the efficacy of the program. When compared
with an educational music control condition at 3, 6, and 9 months post-baseline, those
randomized to the LN will have: H1: Significantly higher mean antiretroviral therapy (ART)
adherence rates (measured by pill counts, self report).
H2: Significantly higher mean levels of ART drug levels in hair sample analyses.
H3: Significantly better clinical indicators: higher mean CD4 lymphocyte counts and
percents, a larger proportion achieving virologic suppression (proportion with HIV RNA PCR
<50 copies/ml), and smaller proportion with evidence of drug resistance, all as measured by
medical record review.
3.0 Explore: a) the effects of LN on symptoms and symptom management; b) the roles of
self-efficacy, outcome expectancies, and personal goal setting as mediators, and depression
and health literacy as moderators of adherence.
Inclusion Criteria:
- HIV+ individuals initiating ART for the first time (except women who may have had ART
during pregnancy); or HIV+ individuals changing ART regimen within the past 3 months
due to side effects or virologic resistance; or HIV+ individuals with a detectable
viral load ≥ 40copies/ml; or HIV+ individuals on ART medication
- English speaking
- Willing to complete 4 assessments
- Willing to complete monthly, unannounced pill counts
- Willing to allow collection of hair samples
- Willing to be randomly assigned to either condition
- Willing to participate in study activities that include using smart phone and mobile
app
Exclusion Criteria:
- Have a history of bilateral hearing loss (health care provider diagnosed or
self-identified)
- Homeless
- Have a cognitive impairment (inability to comprehend the informed consent)
- Display psychotic symptoms, as determined by the Brief Symptom Inventory (BSI)
We found this trial at
1
site
201 Dowman Dr
Atlanta, Georgia 30303
Atlanta, Georgia 30303
(404) 727-6123
Principal Investigator: Marcia M Holstad, DSN
Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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