Written Exposure Therapy for Posttraumatic Stress Disorder
| Status: | Completed |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/17/2019 |
| Start Date: | March 9, 2013 |
| End Date: | April 30, 2018 |
Written Exposure Therapy for Post Traumatic Stress Disorder: A Randomized Noninferiority Trial
Although evidence-based treatments for PTSD exist, a significant minority of individuals do
not benefit from these treatments and many individuals to not seek treatment, citing barriers
such as time commitment and expense of treatment. The goal of the proposed study is to
establish an alternative PTSD treatment that is efficacious and efficient.
not benefit from these treatments and many individuals to not seek treatment, citing barriers
such as time commitment and expense of treatment. The goal of the proposed study is to
establish an alternative PTSD treatment that is efficacious and efficient.
Prior research has demonstrated that written exposure therapy (WET), is an efficient,
well-tolerated, and efficacious treatment for PTSD. The proposed project takes the next step
in establishing WET as an intervention for PTSD by examining whether WET is equally
efficacious to an evidence-based treatment for PTSD. Using a randomized noninferiority
controlled trial, 126 adults diagnosed with PTSD will be assigned to either WET or Cognitive
Processing Therapy (CPT). Outcome data will be collected at baseline and 6-, 12-, 24-, 36-
and 60-weeks post-first treatment session. The primary aim is to examine whether PTSD
participants assigned to WET demonstrate PTSD symptom severity outcome that is noninferior to
PTSD participants assigned to CPT. Secondary aims include examining whether expected
treatment gains are sustained for both treatments and whether WET has a lower treatment
dropout rate relative to CPT. Exploratory aims include examining moderators and mediators of
WET and CPT. If the hypothesis that WET is noninferior to CPT is confirmed then a brief
treatment option for PTSD will be established.
well-tolerated, and efficacious treatment for PTSD. The proposed project takes the next step
in establishing WET as an intervention for PTSD by examining whether WET is equally
efficacious to an evidence-based treatment for PTSD. Using a randomized noninferiority
controlled trial, 126 adults diagnosed with PTSD will be assigned to either WET or Cognitive
Processing Therapy (CPT). Outcome data will be collected at baseline and 6-, 12-, 24-, 36-
and 60-weeks post-first treatment session. The primary aim is to examine whether PTSD
participants assigned to WET demonstrate PTSD symptom severity outcome that is noninferior to
PTSD participants assigned to CPT. Secondary aims include examining whether expected
treatment gains are sustained for both treatments and whether WET has a lower treatment
dropout rate relative to CPT. Exploratory aims include examining moderators and mediators of
WET and CPT. If the hypothesis that WET is noninferior to CPT is confirmed then a brief
treatment option for PTSD will be established.
Inclusion Criteria:
- PTSD diagnosis
- if taking psychotropic medication, on stable dose for 2 months
- Ability to read and write in English
Exclusion Criteria:
- not currently engaged in active PTSD treatment
- no current diagnosis of substance dependence
- no current diagnosis of psychosis
We found this trial at
1
site
Boston, Massachusetts 02130
Principal Investigator: Denise M Sloan, Ph.D.
Phone: 857-364-6333
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