Preoperative Pain Control in Gastric Bypass Surgery Patients
| Status: | Completed |
|---|---|
| Conditions: | Post-Surgical Pain, Hospital |
| Therapuetic Areas: | Musculoskeletal, Other |
| Healthy: | No |
| Age Range: | 18 - 70 |
| Updated: | 4/21/2016 |
| Start Date: | February 2013 |
| End Date: | January 2016 |
A Randomized Placebo-Controlled Study of Whether Pre-operative Pregabalin 300 mg Will Improve Pain Control in Patients Undergoing Laparoscopic Roux-en-Y Gastric Bypass (Bariatric Surgery)
Randomized clinical trial to evaluate whether a single pre-operative dose of Pregabalin will
alleviate post-operative pain and decrease post-operative analgesic requirements in morbidly
obese patients undergoing laparoscopic gastric bypass surgery.
alleviate post-operative pain and decrease post-operative analgesic requirements in morbidly
obese patients undergoing laparoscopic gastric bypass surgery.
Pregabalin is a popular adjunct for relieving neuropathic pain in diabetics. There have been
multiple studies evaluating its use in pre and post-operative pain control in various
surgeries. Post-operative pain control is a challenging problem in bariatric patients due to
the high doses of narcotic required, related to the high body mass, and the danger of
concomitant respiratory depression. In the obese patient, the goal of postoperative pain
management is provision of comfort, early mobilization and improved respiratory function,
without causing inadequate pain control, respiratory compromise or increased nausea.
Methods: A Randomized Controlled Trial, whereby patients undergoing Laparoscopic Roux-en-Y
gastric bypass will be administered a single pre-operative dose of Pregabalin or a placebo.
We plan to follow their immediate post-operative course in the hospital, with regard to the
following primary endpoints:
- Post-operative analgesic requirements
- Post-operative pain scale (rated 0-10)
- Episodes of vomiting
- Post-operative antiemetic requirement
- Length of stay
multiple studies evaluating its use in pre and post-operative pain control in various
surgeries. Post-operative pain control is a challenging problem in bariatric patients due to
the high doses of narcotic required, related to the high body mass, and the danger of
concomitant respiratory depression. In the obese patient, the goal of postoperative pain
management is provision of comfort, early mobilization and improved respiratory function,
without causing inadequate pain control, respiratory compromise or increased nausea.
Methods: A Randomized Controlled Trial, whereby patients undergoing Laparoscopic Roux-en-Y
gastric bypass will be administered a single pre-operative dose of Pregabalin or a placebo.
We plan to follow their immediate post-operative course in the hospital, with regard to the
following primary endpoints:
- Post-operative analgesic requirements
- Post-operative pain scale (rated 0-10)
- Episodes of vomiting
- Post-operative antiemetic requirement
- Length of stay
Inclusion Criteria:
- Patients undergoing laparoscopic Roux-en-Y gastric bypass surgery.
Exclusion Criteria:
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