Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository

Inclusion Criteria:

1. Patient must have a clinical diagnosis of morphea confirmed by the primary
investigator and by histopathological examination.

2. Ages 0-90 years old

3. Children must weigh more than 20 lbs. in order to satisfy Children's Medical Center
policy for the maximum amount of blood drawn in a 24 hour period.

4. Patient or legal guardian must be able to speak and read at a 6th grade reading level.

5. Both male and female patients will be eligible

6. All races and ethnic backgrounds will be included

7. Relationships to proband: All patients with morphea will be included. A patient's
family history will be reviewed and if there is a family history of morphea or
systemic sclerosis then we will give the study patient the investigator's contact
information and ask the family member to call the study team to answer any questions
and enroll them in the study if they choose to do so.

8. Ability to give informed consent: Patients must be able to give informed consent or
they will give assent with parent or guardian consent as a minor to be a part of the
morphea registry.

Exclusion Criteria:

- Patients who have been coded as morphea (701.0), but do not have morphea/localized
scleroderma (examples: steroid atrophy, acquired keratoderma, keloids, nephrogenic
fibrosing dermopathy, systemic sclerosis, lichen sclerosis)