Quality of Life of HIV-infected Participants Switched to Raltegravir Versus Other Antiretroviral Regimens (MK-0518-266)



Status:Completed
Conditions:HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:18 - Any
Updated:10/19/2013
Start Date:November 2012
End Date:October 2013
Contact:Toll Free Number
Phone:1-888-577-8839

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Quality of Life of HIV-infected Patients Switched to Raltegravir Versus Other Antiretroviral Regimens


This is a multi-center, longitudinal observational study of adult human immunodeficiency
virus (HIV) participants at academic and community-based practices in the United States who
are switching from first-line to second-line therapy. The study's primary hypothesis is that
HIV participants switching to raltegravir-based regimens will have better Medical Outcomes
Study-HIV (MOS-HIV) Health Survey scores than participants switched to non-nucleoside
reverse transcriptase inhibitor (NNRTI)-based or protease inhibitor (PI)-based regimens.


Inclusion Criteria:

- Clinical diagnosis of HIV

- Switching antiretroviral regimen(s) for the first time at the start of the study

Exclusion Criteria:

- Currently pregnant

- Presence of active tuberculosis, Hepatitis B, and/or Hepatitis C and receiving
treatment for the condition(s) during the study period

- Presence of active pneumonia or other signs of opportunistic infections at the start
of the study

- Currently participating in a clinical trial
We found this trial at
47
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Charlotte, North Carolina 28205
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303 East Superior Street
Chicago, Illinois 60613
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Washington, District of Columbia 20009
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