BLI1100-202: BLI1100 for the Treatment of Moderate to Severe Acne Vulgaris

Inclusion Criteria:

- Males or females 12 to 45 years of age with facial acne vulgaris

- Qualifying Investigator's Global Assessment severity score

- Qualifying number of non-inflammatory lesions

- Qualifying number of inflammatory lesions

Exclusion Criteria:

- Facial hair (beard), excessive scarring, sunburn or other disfigurement that may
obscure the accurate assessment of acne grade

- Using medications that are reported to exacerbate acne

- Any clinically relevant finding at their baseline physical examination or
dermatological medical history such as severe systemic diseases or diseases of the
facial skin

- Have a known hypersensitivity or previous allergic reaction to any of the components

- Patients who have participated in an investigational clinical, surgical, drug, or
device study within the past 30 days

- Patients who, in the opinion of the investigator, should not be included in the study
for any reason, including inability to follow study procedures