DETECT and Retinal Outcomes in Hypertension



Status:Recruiting
Conditions:Cognitive Studies, High Blood Pressure (Hypertension), Ocular
Therapuetic Areas:Cardiology / Vascular Diseases, Ophthalmology, Psychiatry / Psychology
Healthy:No
Age Range:18 - 65
Updated:2/10/2019
Start Date:November 2012
End Date:January 2020
Contact:Tamara Espinoza, MD
Email:tamara.espinoza@emory.edu

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The Effects of Blood Pressure on Cognitive Function: Examining the Use of Bedside Neuropsychological Testing During Acute Hypertensive Events

The purpose of this study is to study the impact of blood pressure on cognitive performance.

Four groups will be evaluated for possible impact of blood pressure on cognitive performance
and retinal damage.

Inclusion Criteria:

1. Patients triaged to the Grady Memorial Hospital Emergency Department or Marcus Trauma
Unit

2. Age >18 and <65

3. Documented history of hypertension plus one or more of the following:

- current antihypertensive use with controlled blood pressure

- elevated Emergency Department systolic blood pressure or diastolic blood pressure

- OR -

4. Acutely elevated Emergency Department systolic blood pressure or diastolic blood
pressure on 2 separate Emergency Department measurements in the absence of a history
of hypertension

- OR -

5. Normal systolic blood pressure or diastolic blood pressure in the absence of
hypertension.

Exclusion Criteria:

1. Non-English speaking

2. Pre-visit cognitive impairment

3. Physical or psychological impairments that would prohibit comprehension and completion
of DETECT testing

4. Inability to obtain adequate fundoscopic photos

5. Acute intoxication, altered mental status, or head injury within the last 6 months

6. Opiate or benzodiazepine administration by treating providers

7. Clinical condition not allowing testing.
We found this trial at
1
site
80 Jesse Hill Jr Dr SE
Atlanta, Georgia 30303
(404) 616-1000
Grady Memorial Hospital Grady is an internationally recognized teaching hospital staffed exclusively by doctors from...
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mi
from
Atlanta, GA
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