Identify Clinical Conditions That Increase Circulating DNA Levels
| Status: | Completed |
|---|---|
| Conditions: | Cardiology, Infectious Disease, Women's Studies, Endocrine |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Endocrinology, Immunology / Infectious Diseases, Reproductive |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 11/23/2018 |
| Start Date: | October 2012 |
| End Date: | July 28, 2016 |
The investigators are developing a test that is expected to measure the amount of radiation a
patient has been exposed to after a nuclear bomb. The investigator will do this by measuring
the DNA in the patients blood from cells killed by the radiation.
Many diseases and medical conditions can put DNA in the blood. The investigator needs to know
how much DNA in order to better interpret our radiation detection test. Therefore, the
investigator is collecting blood from several patients with different diseases or medical
conditions and also healthy volunteers to measure their DNA content.
Patients that will be included in this study are pregnant women, patients who have suffered a
pulmonary embolism within the past 48 hours, patients who have suffered from myocardial
infarction in the past 48 hours, patients with autoimmune diseases and health patients.
patient has been exposed to after a nuclear bomb. The investigator will do this by measuring
the DNA in the patients blood from cells killed by the radiation.
Many diseases and medical conditions can put DNA in the blood. The investigator needs to know
how much DNA in order to better interpret our radiation detection test. Therefore, the
investigator is collecting blood from several patients with different diseases or medical
conditions and also healthy volunteers to measure their DNA content.
Patients that will be included in this study are pregnant women, patients who have suffered a
pulmonary embolism within the past 48 hours, patients who have suffered from myocardial
infarction in the past 48 hours, patients with autoimmune diseases and health patients.
The investigator will collect 8 mL (one and one half teaspoons) of blood one time only. The
investigator may also collect the patient's past medical history, test results and disease
treatment.
investigator may also collect the patient's past medical history, test results and disease
treatment.
Inclusion Criteria:
1. Patients must be adults in one of the following categories:
- Pregnant
- Suffered a pulmonary embolism within the past 48 hours
- Myocardial infarction in the past 48 hours
- Diagnosed with an autoimmune disease
- Adults age 18-80
- Self-declared healthy adults
2. Patients must be willing to undergo a blood draw
3. Patients must provide study-specific informed consent prior to study entry
Exclusion Criteria:
1. Patients not meeting the above inclusion criteria
We found this trial at
1
site
Gainesville, Florida 32610
Principal Investigator: Paul Okunieff, MD
Phone: 352-265-0680
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