Effect of CPAP on Postoperative Delirium
| Status: | Completed |
|---|---|
| Conditions: | Insomnia Sleep Studies, Neurology, Psychiatric, Pulmonary |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 4/21/2016 |
| Start Date: | June 2013 |
| End Date: | June 2014 |
The Effect of Peri-operative Continuous Positive Airway Pressure (CPAP) on Postoperative Delirium in a Population at High-risk for Obstructive Sleep Apnea (OSA)
Patients with a medical condition known as obstructive sleep apnea may be at increased risk
of delirium following surgery. This study loans autotitrating CPAP machines to
randomly-selected patients who are at high-risk for obstructive sleep apnea with the goal of
preventing post-operative delirium.
of delirium following surgery. This study loans autotitrating CPAP machines to
randomly-selected patients who are at high-risk for obstructive sleep apnea with the goal of
preventing post-operative delirium.
Patients undergoing elective knee and hip replacements will be prospectively enrolled. These
surgical procedures all have an expected length of stay > 3 days. Immediately following
enrollment, patients will be randomized to receive CPAP or routine peri-operative care.
Patients in the CPAP group will be instructed to wear an autotitrating positive airway
pressure (APAP) device any time they sleep prior to surgery and on postoperative days 0, 1,
and 2.
surgical procedures all have an expected length of stay > 3 days. Immediately following
enrollment, patients will be randomized to receive CPAP or routine peri-operative care.
Patients in the CPAP group will be instructed to wear an autotitrating positive airway
pressure (APAP) device any time they sleep prior to surgery and on postoperative days 0, 1,
and 2.
Inclusion Criteria:
- Age 50 and above
- Scheduled for an elective knee or hip replacement
- Ability to speak English and give informed consent
- At risk for obstructive sleep apnea as defined by a STOP-BANG score > 2
Exclusion Criteria:
- History of psychiatric or neurologic illness that would confound delirium assessment
- Severe tracheal or lung disease
- Contraindications to face-mask CPAP
- Treated OSA
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