Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression?
| Status: | Completed |
|---|---|
| Conditions: | Depression, Major Depression Disorder (MDD), Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 55 |
| Updated: | 4/21/2016 |
| Start Date: | March 2013 |
| End Date: | November 2015 |
Genetic Predictors of Response to a Computerized Self-help Program for Depression
The goal of this project is to determine whether genetic information can be used to predict
response to an internet-based treatment of depression. Several studies now indicate that
completing an internet-based treatment for depression, called Deprexis, can significantly
improve symptoms of depression. However, not everyone improves. The purpose of this study is
to determine whether genetic profile can predict who is likely to improve.
response to an internet-based treatment of depression. Several studies now indicate that
completing an internet-based treatment for depression, called Deprexis, can significantly
improve symptoms of depression. However, not everyone improves. The purpose of this study is
to determine whether genetic profile can predict who is likely to improve.
Inclusion Criteria:
- English-speaking
- Have reliable access to the internet (i.e., dialup or broadband access)
- Be willing to donate saliva for DNA research
- Have a current symptoms of depression
- Be stable on medication and/or therapy (i.e. no changes within 2 weeks of study
entry)
Exclusion Criteria:
- Any diagnosis of a psychotic or bipolar disorder
- Meeting for alcohol/drug dependence in the past year
- Having current suicidal risk warranting crisis intervention
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