Ectopic Lipid Deposition and Insulin Resistance in After Treatment of Acromegaly



Status:Completed
Conditions:Skin Cancer, Endocrine
Therapuetic Areas:Endocrinology, Oncology
Healthy:No
Age Range:18 - 75
Updated:6/22/2018
Start Date:April 2013
End Date:March 30, 2016

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This study investigates fat distribution in people with acromegaly. The investigator is also
investigating the change of fat distribution before and after treatment of acromegaly. The
investigator will compare the results of people with acromegaly to the results of healthy
volunteers.


Inclusion Criteria:

- Ages 18 - 75 yr (both groups)

- Study subjects with active acromegaly

- Healthy controls

Exclusion Criteria:

- Serum creatinine or alanine aminotransferase (ALT) > 2 times the upper limit of
normal, metastatic cancer.

- Controls will be receiving no medications and have no chronic diseases, including
cancer, hypertension or diabetes mellitus.

- Contraindications to MRI imaging (both groups) like those with certain metal implants,
surgical clips or pacemakers.

- Pregnant women
We found this trial at
1
site
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
Principal Investigator: Karen Miller, MD
Phone: 617-724-1837
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mi
from
Boston, MA
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