Efficacy of Non Contrast DWI(Diffusion Weighted Imaging) Imaging Compared to DMR-DE
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 4/21/2016 |
| Start Date: | December 2009 |
| End Date: | July 2016 |
Prospective Study to Obtain Preliminary Data to Determine the Efficacy of Non Contrast DWI Imaging Compared to CMR-DE
Use of MRI and DWI to diagnose cardiac scarring after heart attack.
To discover new information about MRI (magnetic resonance imaging) called DWI (diffusion
weighted imaging) and its ability to diagnose cardiac scarring.
CMR-DE (cardiac MR with delayed contrast enhancement) evaluates if there has been scarring
in the heart muscle following a heart attack.
Subjects are injected with a contrast medication that makes the scarring visible if present.
To prove the efficacy of DWI (diffusion weighted imaging) to provide the same images that
CMR-DE (cardiac magnetic resonance with delayed contrast enhancement) provides.
weighted imaging) and its ability to diagnose cardiac scarring.
CMR-DE (cardiac MR with delayed contrast enhancement) evaluates if there has been scarring
in the heart muscle following a heart attack.
Subjects are injected with a contrast medication that makes the scarring visible if present.
To prove the efficacy of DWI (diffusion weighted imaging) to provide the same images that
CMR-DE (cardiac magnetic resonance with delayed contrast enhancement) provides.
Inclusion Criteria:
- Males and females 21 years of age and older
- Healthy volunteers
- subjects with a prior history of heart attack and prior CMR-DE imaging.
Exclusion Criteria:
- Women who are pregnant
- Subjects with GFR < 60 ml/min/1.73m2
- Subjects with ICD
- Subjects with coronary stents incompatible with 3T
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