Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis
| Status: | Recruiting |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 5/5/2018 |
| Start Date: | December 2016 |
| End Date: | December 2019 |
| Contact: | Rosa M Estrada-Y-Martin, MD MSc |
| Email: | rosa.m.estrada.y.martin@uth.tmc.edu |
| Phone: | 713-500-6830 |
Alveolar Dead Space as Predictor of Multi-organ Failure and Mortality in Medical Intensive Care Patients With Sepsis Requiring Mechanical Ventilation
This is an observational study to understand the changes in alveolar dead space in medical
critically ill patients with severe infection (severe sepsis) requiring mechanical
ventilation and the possibility to predict multi-organ failure.
The measurement of alveolar dead space used to require sophisticated equipment and time. New
ventilators have microprocessors that allow rapid mathematical calculation with minimal
intervention.
critically ill patients with severe infection (severe sepsis) requiring mechanical
ventilation and the possibility to predict multi-organ failure.
The measurement of alveolar dead space used to require sophisticated equipment and time. New
ventilators have microprocessors that allow rapid mathematical calculation with minimal
intervention.
The patient will be followed during their ICU stay up to two weeks while on mechanical
ventilation.
Patient will be followed daily for the initial 48 hours and then once per week for 2 weeks
while mechanically ventilated.
ventilation.
Patient will be followed daily for the initial 48 hours and then once per week for 2 weeks
while mechanically ventilated.
Inclusion Criteria:
- Adults with severe sepsis or septic shock on mechanical ventilation
- Enrolled in the initial six hours of ICU admission
Exclusion Criteria:
- Patients with withdrawal or hospice order.
- Patients with terminal, irreversible disease, expect to decease in 48 hours from ICU
admission.
- Patients with COPD.
- Patients transferred from outside ICU with ongoing sepsis management for more than six
hours.
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