Multicenter Trial to Evaluate the Effect of Dapagliflozin on the Incidence of Cardiovascular Events



Status:Completed
Conditions:Cardiology, Diabetes
Therapuetic Areas:Cardiology / Vascular Diseases, Endocrinology
Healthy:No
Age Range:40 - 127
Updated:10/4/2018
Start Date:April 25, 2013
End Date:September 11, 2018

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Dapagliflozin Effect on Cardiovascular Events A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Dapagliflozin 10 mg Once Daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischemic Stroke in Patients With Type 2 Diabetes

This study is being carried out to determine the effect of dapagliflozin on cardiovacular
outcomes when added to current background therapy in patients with type 2 diabetes with
either established cardiovacular disease or cardiovascular risk factors.


Inclusion Criteria:

- Provision of informed consent prior to any study specific procedures

- Female or male aged ≥40 years

- Diagnosed with Type 2 Diabetes

- High Risk for Cardiovascular events

Exclusion Criteria:

- Diagnosis of Type 1 diabetes mellitus History of bladder cancer or history of
radiation therapy to the lower abdomen or pelvis at any time

- Chronic cystitis and/or recurrent urinary tract infections

- Pregnant or breast-feeding patients
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