Physiological Response of Cortisol to Cardiac Catheterization



Status:Completed
Conditions:Endocrine
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:20 - 90
Updated:2/8/2015
Start Date:March 2013
End Date:June 2014
Contact:Valentina Tarasova, MD
Email:ValentinaTarasova1@creighton.edu
Phone:402-280-4470

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Cortisol is essential for survival. The importance of cortisol response is most apparent in
patients with partial or complete deficiency of glucocorticoids during stressful events such
as illness or surgery.

It is known that cortisol and other stress hormones increase during acute myocardial
infarction as well (9-11). Cardiac catheterization is an essential tool for the management
of acute coronary syndrome, and for the evaluation of the burden of coronary artery disease
in cardiac patients.

Inclusion Criteria:

- Patients undergoing elective cardiac catheterization, who are willing and able to
give consent.

Exclusion Criteria:

- • Patients with .primary or secondary adrenal insufficiency.

- Patients taking steroids in the doses equivalent of at least 5 mg of prednisone
daily for more than 3 weeks in the previous year.

- Patients undergoing cardiac catheterization in the setting of acute coronary
syndrome, eg. STEMI, NSTEMI and unstable angina.

- Patients with low albumin level (<3.5 g/dL)
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