Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit



Status:Active, not recruiting
Conditions:Post-Surgical Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:Any
Updated:3/2/2019
Start Date:April 2013
End Date:May 2019

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Parent/Nurse Controlled Analgesia for Post-Operative Pain Management in Neonates: A Preliminary Randomized Controlled Trial

The aim of this study is to examine the safety and effectiveness of 2 morphine delivery
systems for post-surgical neonates. The investigators hypothesize that this study will be
feasible to conduct, and that neonates receiving morphine via a Parent/Nurse Controlled
Analgesia pump will receive less morphine and experience fewer side effects than neonates
receiving morphine via continuous opioid infusion.


Inclusion Criteria:

- Surgery Location:

- Abdominal or Thoracic

- First surgery only

Age:

- Born ≥ 34-44 weeks post-menstrual age

- Weight: Weight at birth or current weight ≥2 kg Intubated or extubated

Prior opioid exposure:

- < 2 days of continuous exposure

- if history of > 2 day continuous exposure, must be off continuous drip for a week

- Intermittent exposure ≤ 2 days prior to surgery Neonates exposed to chronic opioids in
utero *In utero exposure to Selective Seretonin Reuptake Inhibitors and illicit drugs
will be screened for and annotated.

At least 1 parent is English-speaking

Exclusion Criteria:

- Surgery Type:

- Cardiac, Patent Ductus Arteriosus Ligation; Omphalocele (if intubated
pre-operatively)

Diagnoses:

• Necrotizing Enterocolitis; Diaphragmatic hernia (unless thoracoscopically repaired);
Chemically or physiologically paralyzed Receiving vasopressors Receiving acetaminophen or a
benzodiazepine (lorazepam or midazolam) ≤ 24 h before surgery Patients with any of the
following: Epidural; Oscillating ventilator
We found this trial at
1
site
9000 W Wisconsin Ave #270
Milwaukee, Wisconsin 53226
(414) 266-2000
Children's Hospital of Wisconsin Nothing matters more than our children. At Children's Hospital of Wisconsin,...
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from
Milwaukee, WI
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