Effectiveness of Biofreeze® on Shoulder Pain and In-office Exercise Performance

Biofreeze® is a topical analgesic, frequently used in the office or given to a patient for
home use as a way to mitigate pain during the course of treatment. Rehabilitative exercises
are considered an important component of care for shoulder pain patients, although pain can
be a limiting factor in the advancement of rehabilitation. The purpose of this study is to
evaluate the addition of Biofreeze® to an in-office group of shoulder pain patients to
determine its impact on pain reduction. Methods: Patients 18-64 years old with mechanical
shoulder pain who are candidates for standard shoulder therapy will be randomized into two
groups (N=20). The Control group (N=10) will receive standard shoulder therapy alone while
the Intervention group (N=10) will receive standard shoulder therapy plus Biofreeze® just
prior to initiating the in-office exercise program. Values of pain (NPRS) and disability
(ASES) will be recorded at baseline, 2 weeks, and 4 weeks. Hypotheses will be addressed by
repeated measures ANOVAs within and between group, time, and interaction main effects.
Clinical Relevance: Progression of therapeutic exercises can be limited by pain and the
associated disability. The ability to decrease shoulder pain and disability with a topical
analgesic will allow health care professionals to advance patients through a therapeutic
exercise program without the restriction of pain. In turn, patients will correct the
underlying condition of their shoulder pain at a faster rate.