A 12 Week Study of QVA149 Compared to Fluticasone/Salmeterol (Advair) for Treatment of COPD



Status:Completed
Conditions:Chronic Obstructive Pulmonary Disease, Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:10/3/2013
Start Date:July 2013
End Date:March 2014
Contact:Novartis Pharmaceuticals
Phone:1-888-669-6682

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A 12-week Treatment, Multi-center, Randomized, Double-blind, Double-dummy, Parallel-group Study to Assess the Efficacy, Safety and Tolerability of QVA149 Compared to Fluticasone/Salmeterol in COPD Patients With Moderate to Severe Airflow Limitation


Study is to show that QVA149 is superior to the standard of care, fluticasone/salmeterol, in
patients with moderate to severe airflow limitation


Inclusion Criteria:

- Age >= 40 years, patients with airflow limitation indicated by post-bronchdilation
FEV1 >=30% and <80% of predicted normal, current or ex-smokers with a 10 pack year
smoking history, patients with a mMRC grade 2 or greater

Exclusion Criteria:

- prolonged QTCF >450 ms, paroxysmal atrial fibrillation, Type I or uncontrolled Type
II diabetes, history of asthma, COPD diagnosis before age 40, receiving treatments
not allowed in the study, other concomitant pulmonary diseases.

Other protocol-defined inclusion/exclusion criteria may apply.
We found this trial at
20
sites
Novartis
Portland, Oregon 97228
Novartis Novartis, which was created in 1996 by the merger of the Swiss companies Ciba-Geigy...
?
mi
from
Portland, OR
Click here to add this to my saved trials
Novartis Investigative Site
Abingdon, Virginia 24210
?
mi
from
Abingdon, VA
Click here to add this to my saved trials
Novartis Investigative site
Aurora, Colorado 80010
?
mi
from
Aurora, CO
Click here to add this to my saved trials
Novartis Investigative Site
Brick, New Jersey 08724
?
mi
from
Brick, NJ
Click here to add this to my saved trials
Novartis Investigative Site
Cincinatti, Ohio 45219
?
mi
from
Cincinatti, OH
Click here to add this to my saved trials
Novartis Investigative site
Dallas, Texas 75216
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Novartis Investigative site
Gainesville, Georgia 30501
?
mi
from
Gainesville, GA
Click here to add this to my saved trials
Novartis Investigative Site
Hartford, Connecticut 06106
?
mi
from
Hartford, CT
Click here to add this to my saved trials
Novartis Investigative Site
High Point, North Carolina 27262
?
mi
from
High Point, NC
Click here to add this to my saved trials
Novartis Investigative Site
Kalispell, Montana 59901
?
mi
from
Kalispell, MT
Click here to add this to my saved trials
Novartis Investigative Site
Knoxville, Tennessee 37934
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
Novartis Investigative Site
Las Vegas, Nevada 89135
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Novartis Investigative site
Los Angeles, California 90095
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Novartis Investigative Site
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
Novartis Investigative Site
Mt. Pleasant, South Carolina 29464
?
mi
from
Mt. Pleasant, SC
Click here to add this to my saved trials
Novartis Investigative Site
Oklahoma City, Oklahoma 73104
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Novartis Investigative Site
Omaha, Nebraska 68144
?
mi
from
Omaha, NE
Click here to add this to my saved trials
Novartis Investigative Site
Phoenix, Arizona 85012
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Novartis Investigative Site
Spokane, Washington 99202
?
mi
from
Spokane, WA
Click here to add this to my saved trials
Novartis Investigative Site
St Louis, Missouri 63104
?
mi
from
St Louis, MO
Click here to add this to my saved trials