Effect of Tetrabenazine on Stroop Interference in HD
| Status: | Completed |
|---|---|
| Conditions: | Neurology |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/17/2018 |
| Start Date: | March 2013 |
| End Date: | January 1, 2018 |
Effect of Tetrabenazine on Stroop Interference in Huntington Disease
Tetrabenazine has been shown to improve gating of abnormal visual stimuli and improve
postural stability in Huntington disease (HD) patients as measured by computerized dynamic
posturography testing. This study aims to elucidate whether partial dopaminergic depletion
via low dose tetrabenazine has a similar effect on masking out of abnormal visual stimuli on
the Stroop interference test.
postural stability in Huntington disease (HD) patients as measured by computerized dynamic
posturography testing. This study aims to elucidate whether partial dopaminergic depletion
via low dose tetrabenazine has a similar effect on masking out of abnormal visual stimuli on
the Stroop interference test.
Inclusion Criteria:
- Established diagnosis of Huntington disease by movement disorders expert
- Patients currently taking tetrabenazine.
- Patients should not have taken dopamine receptor blocking medication for at least
three days
Exclusion Criteria:
We found this trial at
1
site
New York, New York 10029
Principal Investigator: Robert Fekete, MD
Phone: 212-360-3711
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