Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa

Inclusion Criteria:

- Hidradenitis suppurativa (HS) (moderate to severe)

- Diagnosis of HS for at least 1 year

- At least 5 active inflammatory lesions in at least 2 locations

- On a stable dose of antibiotics and/or analgesics for at least 4 weeks (if already
taking these medications)

- Average pain score of 3-9.

Exclusion Criteria:

- History of cyclic neutropenia

- Laboratory assessment abnormalities

- Underlying disorder considered unsuitable for inclusion

- Other skin diseases that may interfere with HS assessment

- Pregnancy or planning for pregnancy