Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo



Status:Recruiting
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - 65
Updated:3/17/2019
Start Date:July 26, 2006
End Date:November 11, 2019
Contact:Pfizer CT.gov Call Center
Email:ClinicalTrials.gov_Inquiries@pfizer.com
Phone:1-800-718-1021

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Trial Summary
Trial Overview
Inclusion Criteria

PROSPECTIVE RANDOMIZED 12-WEEK CONTROLLED STUDY OF VISUAL FIELD CHANGE IN SUBJECTS WITH PARTIAL SEIZURES RECEIVING PREGABALIN OR PLACEBO

Patients with partial seizures currently taking 1-3 antiepileptic medications will have a
50:50 chance to receive Lyrica 300 mg per day or placebo (no active ingredients) added on to
their current medications for 3 months. Neither the study doctor nor the patient will know
the medication assignment. Vision testing will be performed prior to receiving the study
treatment and at the end of the study to see if there are any changes.


Inclusion Criteria:

- Epilepsy partial seizure subjects.

- Currently taking 1 to 3 antiepileptic drugs.

Exclusion Criteria:

- Pre-existing eye diseases (glaucoma).

- Insufficient response to pregabalin in the treatment of partial seizure, or patients
currently receiving pregabalin treatment.
We found this trial at
115
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Center for Brain and Neuro Care
Fulton, Maryland 20759
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Bradenton Research Center
3924 9th Avenue West
Bradenton, Florida 34205
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Cleveland Clinic
9500 Euclid Avenue
Cleveland, Ohio 44106
216.444.2200
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Wayne State University
5050 Anthony Wayne Dr
Detroit, Michigan 48201
(313) 577-2424
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NEA Baptist Clinic - Clinical Research Center
416 East Washington Avenue
Jonesboro, Arkansas 72401
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University of Arkansas for Medical Sciences
529 West Markham Street
Little Rock, Arkansas 72205
(501) 686-7000
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Neuromedical Clinic of Central Louisiana
Alexandria, Louisiana 71301
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Louisiana Eye and Laser Center
Alexandria, Louisiana 71303
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Dent Neurosciences Research Center
Amherst, New York
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Western New York Ophthalmology Group
Amherst, New York 14226
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Coastal Research Associates, LLC
Atlanta, Georgia 30339
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FutureSearch Trials of Neurology
Austin, Texas 78703
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Texan Eye
Austin, Texas 78731
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University of Maryland Eye Associates, P.A.
Baltimore, Maryland 21201
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University of Maryland School of Medicine
655 West Baltimore Street
Baltimore, Maryland 21201
(410) 706-7410
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University of Maryland
Baltimore, Maryland 20742
(301) 405-1000
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Daniel J. Nadler, MD, PC
Beaver, Pennsylvania 15009
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Heritage Valley Health System
Beaver, Pennsylvania 15009
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Beth Israel Deaconess Medical Center (BIDMC)
Boston, Massachusetts 02215
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Massachusetts Eye & Ear Infirmary
243 Charles St
Boston, Massachusetts 02114
(617) 523-7900
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The Eye Associates of Manatee, LLP
Bradenton, Florida 34209
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Buffalo General Hospital
Buffalo, New York
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The Jacobs Neurological Institute Comprehensive Epilepsy Center
Buffalo, New York 14209
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MetroHealth Med Ctr
2500 Metrohealth Dr
Cleveland, Ohio 44109
(216) 778-7800
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Glaucoma Plus Eye Care, LLC
Columbia, Maryland 21044
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CCN-MS & Neurology Associates
Columbia, Missouri 65401
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University of Missouri
Columbia, Missouri 65211
(573) 882-2121
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Ohio State University Medical Center
Columbus, Ohio 43210
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Barbara Swartz, MD, Inc
Costa Mesa, California 92627
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Glaucoma Associates of Texas
Dallas, Texas 75231
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Texas Neurology, PA
Dallas, Texas 75214
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SJS Clinical Research, Inc.
Destin, Florida 32541
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Harper Hospital
Detroit, Michigan 48201
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Jeffrey Shaver, MD
Edmond, Oklahoma 73013
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Tammy Holsclaw-Jones, OD, PLLC
210 Rogosin Drive
Elizabethton, Tennessee 37643
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Institute of Neurological Care
Englewood Cliffs, New Jersey 07632
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Clinical Trials of America
Eugene, Oregon 97401
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Oregon Eye Consultants, LLC
Eugene, Oregon 97401
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Pacific Women's Center, LLC
Eugene, Oregon 97401
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White Wilson Medical Center
Fort Walton Beach, Florida 32547
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Frazer Eye Care Center
Fraser, Michigan 48026
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Mireille P. Hamparian
Glendale, California 91206
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Minneapolis Clinic of Neurology
Golden Valley, Minnesota 55422
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Guilford Neurologic Associates, Inc.
Greensboro, North Carolina 27405
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Digby Eye Associates
Greensboro, North Carolina 27408
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Center For Advanced Eye Care
7 Pointe Circle
Greenville, South Carolina 29615
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Premier Neurology, PC
420 The Parkway
Greer, South Carolina 29650
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Bergman Eye Associates
Hagerstown, Maryland 21740
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Neurology Consultant, P.A.
Hagerstown, Maryland 21740
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The Center for Clinical Research
Hagerstown, Maryland 21740
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Egret Bay Neurology
Houston, Texas 77058
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Lakeside Vision Center
Irvine, California 92604
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The Reeves Eye Institute, PLLC
Johnson City, Tennessee 37604
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Tri-State Mountain Neurology Associates
Johnson City, Tennessee 37604
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NEA Baptist Clinic
Jonesboro, Arkansas 72401
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NEA Baptst Clinic
Jonesboro, Arkansas 72401
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Nevada Eye Care
2090 East Flamingo Road
Las Vegas, Nevada 89119
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Neurology Center of Las Vegas
Las Vegas, Nevada 89128
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Chenal MRI
Little Rock, Arkansas 72205
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Clinical Trials, Inc.
Little Rock, Arkansas 72205
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Eye Care Arkansas
Little Rock, Arkansas 72205
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Radiology Consultants
Little Rock, Arkansas 72205
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Eye Treatment Center, Inc.
Long Beach, California 90813
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DeHaven Eye Clinic
Longview, Texas 75601
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Diagnostic Clinic of Longview Center for Clinical Research
Longview, Texas 75605
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Diagnostic Clinic of Longview, PA
Longview, Texas 75605
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Semmes Murphey Clinic
Memphis, Tennessee 38104
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Memphis, Tennessee 38163
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Harper Hospital-MRI
3990 John R Street
MI, Michigan 48201
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Pharmax Research Clinic
Miami, Florida 33126
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Dr. Raul F. Masvidal, MD, PA
Miami, Florida 33134
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Medical College of Wisconsin Department of Neurology Froedtert Memorial Hospital
Milwaukee, Wisconsin 53226
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Medical College of Wisconsin, The Eye Institute
Milwaukee, Wisconsin 53226
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Neurology Center, P.C.
Mobile, Alabama 36607
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Premier Medical Group
Mobile, Alabama 36608
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Valley Neurological Associates
Monaca, Pennsylvania 15061
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Coastal Carolina Research Center
Mount Pleasant, South Carolina 29464
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Glaucoma Consultants and Center for Eye Research, PA
721 Long Point Road
Mount Pleasant, South Carolina 29464
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Tidewater Neurology
913 Bowman Road
Mount Pleasant, South Carolina 29464
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Yale Eye Center
New Haven, Connecticut 06510
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Yale-New Haven Hospital
20 York St, N20 York St,
New Haven, Connecticut 06520
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Yale Neurology Clinic
New Haven, Connecticut 06519
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Yale University School of Medicine
333 Cedar St
New Haven, Connecticut 06504
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Hoag Memorial Hospital Presbyterian
Newport Beach, California 92658
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Neurology Clinic PC
Northport, Alabama 35476
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Sooner Clinical Research
Oklahoma City, Oklahoma 73112
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Helm Vision Group
619 West Avenue Q
Palmdale, California 91355
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Clinical Innovations Inc.
Paramount, California 90723
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Office of Patricia Burke, MD
Paramus, New Jersey 07652
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David M Klein, MD, PA
Port Charlotte, Florida 33948
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Medsol Clinical Research Center
Port Charlotte, Florida 33952
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Neurological Associates, Inc.
Richmond, Virginia 23226
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Care Access Research
Santa Clarita, California 91321
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Valencia Neurology Medical Group
Santa Clarita, California 91321
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Intercoastal Medical Research Center
Sarasota, Florida 34232
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Dr. Nicholas Monsul
Sarasota, Florida 34239
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Sarasota Retinal Institute
Sarasota, Florida 34239
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Sofia, 1408
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