Laboratory Study of Cannabidiol on the Effects of Smoked Marijuana
| Status: | Completed |
|---|---|
| Conditions: | Smoking Cessation, Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 4/2/2016 |
| Start Date: | May 2013 |
| End Date: | September 2013 |
Laboratory Study of the Influence of Oral Cannabidiol on the Subjective, Reinforcing and Cardiovascular Effects of Smoked Marijuana
The objective of this study is to assess the effects of oral cannabidiol (CBD; 0, 200, 400,
800 mg) on smoked marijuana's (0, 5.6% THC) subjective, reinforcing, cognitive, and
cardiovascular effects. This experiment is expected to reveal CBD's intrinsic effects when
combined with placebo marijuana, as well as its ability to modulate the behavioral effects
of active marijuana.
800 mg) on smoked marijuana's (0, 5.6% THC) subjective, reinforcing, cognitive, and
cardiovascular effects. This experiment is expected to reveal CBD's intrinsic effects when
combined with placebo marijuana, as well as its ability to modulate the behavioral effects
of active marijuana.
Inclusion Criteria:
- Adults between the ages of 18 and 50.
- Current marijuana use: Minimum of four times per week, 0.5 joints per occasion during
the preceding 4 weeks.
- Able to perform study procedures
- Women practicing an effective form of birth control
Exclusion Criteria:
- Female subjects who are currently pregnant or breastfeeding.
- Current, repeated illicit drug use other than marijuana
- Presence of significant medical illness
- History of heart disease
- Request for drug treatment
- Current parole or probation
- Recent history of significant violent behavior
- Major psychiatric disorder
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Charleston, South Carolina 29425
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