Prone Patient Positioning in Reducing Tumor Motion and Improving Breathing Reproduction in Patients With Lung Cancer Undergoing Radiation Therapy
| Status: | Terminated |
|---|---|
| Conditions: | Lung Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | May 2010 |
| End Date: | September 2015 |
Pulmonary Tumor Motion Reduction and Improved Breathing Reproducibility by Prone Patient Positioning in Radiation Therapy
This clinical trial studies prone patient positioning in reducing tumor motion and improving
breathing reproduction in patients with lung cancer undergoing radiation therapy. Prone
patient positioning during radiation therapy may help kill tumor cells without harming
normal tissue.
breathing reproduction in patients with lung cancer undergoing radiation therapy. Prone
patient positioning during radiation therapy may help kill tumor cells without harming
normal tissue.
PRIMARY OBJECTIVES:
I. Quantify the three-dimensional tumor and normal tissue (thoracic and abdominal) motion,
deformation and volume changes with the respiratory cycle during imaging in prone vs. supine
positioning.
II. Quantify the three-dimensional tumor and normal tissue (thoracic and abdominal) motion,
deformation and volume changes with the respiratory cycle and alterations thereof during a
radiotherapy series.
OUTLINE:
Patients undergo one conventional computed tomography (CT) scan and one 4 dimensional CT (4D
CT) scan in both supine and prone positioning before undergoing radiation therapy.
I. Quantify the three-dimensional tumor and normal tissue (thoracic and abdominal) motion,
deformation and volume changes with the respiratory cycle during imaging in prone vs. supine
positioning.
II. Quantify the three-dimensional tumor and normal tissue (thoracic and abdominal) motion,
deformation and volume changes with the respiratory cycle and alterations thereof during a
radiotherapy series.
OUTLINE:
Patients undergo one conventional computed tomography (CT) scan and one 4 dimensional CT (4D
CT) scan in both supine and prone positioning before undergoing radiation therapy.
Inclusion Criteria:
- Measurable disease on the planning computed tomography (CT) scan
- Patients with lung cancer visible on fluoroscopic imaging or planning CT who are
scheduled to receive external beam radiation treatment will be eligible for this
study
Exclusion Criteria:
- Patients requiring continuous supplemental oxygen due to the requirement of
spirometry during all imaging studies
- Pregnant females
We found this trial at
1
site
401 College Street
Richmond, Virginia 23298
Richmond, Virginia 23298
(804) 828-0450
Virginia Commonwealth University Massey Cancer Center Founded in 1974, VCU Massey Cancer Center is a...
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