Cangrelor Prasugrel Transition Study
Status: | Completed |
---|---|
Conditions: | Peripheral Vascular Disease, Cardiology |
Therapuetic Areas: | Cardiology / Vascular Diseases |
Healthy: | No |
Age Range: | 18 - 75 |
Updated: | 11/30/-0001 |
Start Date: | June 2013 |
End Date: | July 2013 |
A Study of the Transition From IV Cangrelor to Oral Prasugrel, and Prasugrel to Cangrelor, in Patients With Coronary Artery Disease.
To demonstrate that patients treated with cangrelor can be directly switched to oral
prasugrel and that patients treated with prasugrel can be switched to cangrelor without a
significant decrease in the extent of inhibition of platelet aggregation.
Inclusion Criteria:
1. greater than / equal to 18 and less than 75 years of age
2. stable coronary artery disease defined by the following criteria
1. Previous myocardial infarction defined by admission to the hospital with
elevation of markers of injury or the presence of pathologic Q waves on at least
2 contiguous electrocardiogram (ECG) leads.
OR
2. Previous revascularization by PCI or CABG. AND
3. Treatment with ASA 81 mg daily.
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