Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty

Inclusion Criteria:

- At least 18 years of age

- Male or female patient who had endothelial keratoplasty procedure within the past 1
to 7 weeks

- Patient is able and willing to administer eye drops

- Patient is able to comprehend and has signed the Informed Consent form.

- Patient is likely to complete the one-year course of the study

Exclusion Criteria:

- A history of a previous rejection episode in the study eye

- A patient exhibiting intraocular inflammation

- A patient with a known sensitivity to any of the ingredients in the study medications

- A patient who has a condition (i.e., UNCONTROLLED systemic disease) or is in a
situation which in the investigator's opinion may put the patient at significant
risk, may confound the study results, or may interfere significantly with the
patient's participation in the study

- A patient with abnormal eyelid function.

- A patient that is exhibiting active corneal ulceration, keratitis, or conjunctivitis,
or who has a history of herpetic keratitis.

- Presence of any ocular disease that would interfere with the evaluation of the study
treatment. However, patients with a history of cystoid macular edema, age-related
macular degeneration, controlled glaucoma, corneal neovascularization, and other
non-interfering comorbidities may be enrolled.

- A patient with a history of non-compliance with using prescribed medication.

- A patient who is concurrently involved in or participated in another randomized
clinical trial within 30 days prior to enrollment in this study.

- Patients who are pregnant or planning to become pregnant within the duration of the
study