Enteral Feeding in the Post-Injury Open Abdomen
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 98 |
| Updated: | 4/17/2018 |
| Start Date: | January 2013 |
| End Date: | January 2020 |
| Contact: | Clay Cothren, MD |
| Email: | clay.cothren@dhha.org |
| Phone: | 303-436-6558 |
The purpose of this study is to determine if Enteral Feeding (EN) in patients with a
traumatic bowel injury requiring an open abdomen impacts outcomes. Patients who receive EN
will be compared to those who remain nil-per-os (NPO). Additionally, an internal study
control will be performed by analyzing concurrent injured patients requiring an open abdomen
who did not have a bowel injury.
Specific aims:
Hypothesis 1: EN in patients with a traumatic bowel injury requiring an open abdomen improves
fascial closure rate compared to patients who remain NPO.
Hypothesis 2: EN in patients with a traumatic bowel injury requiring an open abdomen reduces
infectious complications compared to patients who remain NPO.
Hypothesis 3: EN in patients with a traumatic bowel injury requiring an open abdomen have a
lower mortality rate compared to patients who remain NPO.
traumatic bowel injury requiring an open abdomen impacts outcomes. Patients who receive EN
will be compared to those who remain nil-per-os (NPO). Additionally, an internal study
control will be performed by analyzing concurrent injured patients requiring an open abdomen
who did not have a bowel injury.
Specific aims:
Hypothesis 1: EN in patients with a traumatic bowel injury requiring an open abdomen improves
fascial closure rate compared to patients who remain NPO.
Hypothesis 2: EN in patients with a traumatic bowel injury requiring an open abdomen reduces
infectious complications compared to patients who remain NPO.
Hypothesis 3: EN in patients with a traumatic bowel injury requiring an open abdomen have a
lower mortality rate compared to patients who remain NPO.
Fascial closure is determine by the primary physician and should be recorded in the operative
record. This record will be accessed to determine if this variable is accomplished.
Additionally, any dehiscence complication will be recorded (which would impact the long-term
fascial closure rate). Infectious complications (abscess, pneumonia, etc) will be adjudicated
by the primary clinician and any record of this in the patient chart will be recorded.
record. This record will be accessed to determine if this variable is accomplished.
Additionally, any dehiscence complication will be recorded (which would impact the long-term
fascial closure rate). Infectious complications (abscess, pneumonia, etc) will be adjudicated
by the primary clinician and any record of this in the patient chart will be recorded.
Inclusion Criteria:
- All patients with a post-injury open abdomen
Exclusion Criteria:
- Patients to be excluded from analysis include deaths within 24 hours, identification
of injury > 24 hours, and those transferred from an outside hospital > 24 hours
following initial injury.
We found this trial at
1
site
777 Bannock St
Denver, Colorado 80204
Denver, Colorado 80204
(303) 436-6000
Principal Investigator: Clay Cothren Burlew, MD
Denver Health Medical Center Denver Health is a comprehensive, integrated organization providing level one care...
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