GLP-1 and Hypoglycemia
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Endocrine, Diabetes |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 5/9/2018 |
| Start Date: | July 2013 |
| End Date: | December 2018 |
Hypoglycemia Associated Autonomic Dysfunction
Low blood sugar can negatively affect how blood vessels function, and this can lead to an
increase in the risk for heart attacks, strokes and other problems related to the stiffening
and blockage of blood vessels. The purpose of this study is to learn if and how glucagon-like
peptide-1 (GLP-1; a naturally occurring hormone in the gut) changes the effects that low
blood sugar levels have on blood vessels.
increase in the risk for heart attacks, strokes and other problems related to the stiffening
and blockage of blood vessels. The purpose of this study is to learn if and how glucagon-like
peptide-1 (GLP-1; a naturally occurring hormone in the gut) changes the effects that low
blood sugar levels have on blood vessels.
Inclusion Criteria:
- 14 (7 males, 7 females) healthy controls age 30-60 yr.
- 14 (7 males, 7 females) people with type 2 DM age 30-60 yr.
- For type 2 DM: HbA1c 6-10.0%
- No significant diabetic tissue complications (i.e. history of retinopathy, neuropathy,
stasis ulcers, etc.)
- Body mass index >25kg • m-2
Exclusion Criteria:
We found this trial at
1
site
621 West Lombard Street
Baltimore, Maryland 21201
Baltimore, Maryland 21201
(410) 706-7101
Principal Investigator: Stephen N Davis, MBBS
Phone: 410-706-5643
University of Maryland, Baltimore Welcome to the University of Maryland, Baltimore (UMB) founded in 1807...
Click here to add this to my saved trials
