Adherence Enhancement for Renal Transplant Patients
| Status: | Completed |
|---|---|
| Conditions: | High Blood Pressure (Hypertension), Renal Impairment / Chronic Kidney Disease |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Nephrology / Urology |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 4/2/2016 |
| Start Date: | September 2011 |
| End Date: | June 2013 |
| Contact: | john w mcgillicuddy, md |
| Email: | mcgillij@musc.edu |
| Phone: | 843.792.3368 |
Despite significant advances in the care of kidney transplant recipients, long term graft
survival after renal transplantation remains suboptimal. Medication nonadherence and
clinical inertia are key contributors to graft loss. The purpose of the proposed RCT
feasibility study is to evaluate impact of a "bundled" wireless real time medication
reminder system and blood pressure monitoring system in combination with a cognitive
behavioral adherence skills enhancement program upon medication adherence, therapeutic drug
concentration, and blood pressure, in nonadherent kidney transplant recipients with
hypertension. We propose to recruit 60 kidney transplant recipients in phase 1 with 20
non-adherent continuing to phase 2 for a 5-month feasibility RCT.
survival after renal transplantation remains suboptimal. Medication nonadherence and
clinical inertia are key contributors to graft loss. The purpose of the proposed RCT
feasibility study is to evaluate impact of a "bundled" wireless real time medication
reminder system and blood pressure monitoring system in combination with a cognitive
behavioral adherence skills enhancement program upon medication adherence, therapeutic drug
concentration, and blood pressure, in nonadherent kidney transplant recipients with
hypertension. We propose to recruit 60 kidney transplant recipients in phase 1 with 20
non-adherent continuing to phase 2 for a 5-month feasibility RCT.
Inclusion Criteria:
- Persons > 21 years of age
- first time recipient of a solitary kidney transplant
- prescribed at least 3 medications for immunosuppression and hypertension
- previous history of non-adherence
- functioning kidney transplant
- ability to speak, hear and understand English
- able to use medication delivery device and self administer medications
- able to operate blood pressure monitor
- comfortable using cell phone
- no other diagnosis that might shorten lifespan
- transplant physician's assent that the patient can participate
Exclusion Criteria:
- failure to meet all inclusion criteria
We found this trial at
1
site
171 Ashley Avenue
Charleston, South Carolina 29425
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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