An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension



Status:Recruiting
Conditions:High Blood Pressure (Hypertension)
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - 75
Updated:1/12/2019
Start Date:May 2012
End Date:August 2021

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Trial Summary
Trial Overview
Inclusion Criteria

Open-Label Extension Study of UT-15C in Subjects With Pulmonary Arterial Hypertension- A Long-Term Follow-Up to Protocol TDE-PH-310

This study is an international, multi-center, open-label study designed to provide oral
treprostinil (UT-15C) to eligible subjects with pulmonary arterial hypertension who have
completed the TDE-PH-310 study. The purpose of this study is to assess the long-term safety
of UT-15C and to assess the effects of long-term treatment with UT-15C on exercise capacity.


Inclusion Criteria:

- Participated in United Therapeutics Study TDE-PH-310

Exclusion Criteria:

- Premature discontinuation of United Therapeutics Study TDE-PH-310 due to reasons other
than clinical worsening
We found this trial at
39
sites
University of California-Davis Medical Group, Advanced Lung Disease/Transplant Program
Sacramento, California 95817
Principal Investigator: Roblee Allen, MD
Phone: 916-734-1554
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Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
Principal Investigator: Aaron Waxman, MD, PhD
Phone: 617-525-9731
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Boston, MA
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Tufts Medical Center
800 Washington St
Boston, Massachusetts 02111
(617) 636-5000
Principal Investigator: Nicholas Hill, MD
Phone: 617-636-1334
Tufts Medical Center Tufts Medical Center is an internationally-respected academic medical center – a teaching...
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Boston, MA
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University of Florida
Gainesville, Florida 32610
(352) 392-3261
Principal Investigator: Hassan Alnuaimat
Phone: 352-273-8990
University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
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Gainesville, FL
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University of Texas Health Science Center at Houston
7000 Fannin St
Houston, Texas 77030
(713) 500-4472
Principal Investigator: Bela Patel, MD
Phone: 713-500-6851
University of Texas Health Science Center at Houston The University of Texas Health Science Center...
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Houston, TX
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Cedars-Sinai Medical Center
8700 Beverly Blvd # 8211
Los Angeles, California 90048
(1-800-233-2771)
Principal Investigator: Antoine Hage
Phone: 310-248-7134
Cedars Sinai Med Ctr Cedars-Sinai is known for providing the highest quality patient care. Our...
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Los Angeles, CA
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Oregon Health and Science University
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Principal Investigator: Akram Khan, MD
Phone: 503-494-9570
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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Portland, OR
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Rhode Island Hospital
593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Principal Investigator: James Klinger, MD
Phone: 401-444-9097
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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Providence, RI
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University of Rochester
60 Crittenden Blvd # 70
Rochester, New York 14642
(585) 275-2121
Principal Investigator: R. James White, M.D., Ph.D.
Phone: 585-486-0869
University of Rochester The University of Rochester is one of the country's top-tier research universities....
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Rochester, NY
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Cleveland Clinic Florida
2950 Cleveland Clinic Blvd.
Weston, Florida 33331
866.293.7866
Principal Investigator: Franck Rahaghi, MD
Phone: 954-659-6213
Cleveland Clinic Florida Cleveland Clinic Florida, located in Weston, West Palm Beach, Palm Beach Gardens...
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Weston, FL
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Asheville Cardiology Associates
Asheville, North Carolina 28802
Principal Investigator: Benjamin Trichon, MD
Phone: 828-274-6000
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Asheville, NC
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Emory University Hospital
1364 Clifton Rd NE
Atlanta, Georgia 30322
(404) 712-2000
Principal Investigator: Micah Fisher, MD
Phone: 404-712-7458
Emory University Hospital As the largest health care system in Georgia and the only health...
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Atlanta, GA
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Augusta University
Augusta, Georgia 30912
Principal Investigator: Clark McDonough, MD
Phone: 706-721-9680
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Augusta, GA
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University of Colorado Hospital
12605 East 16th Avenue
Aurora, Colorado 80045
720-848-0000
Principal Investigator: David Badesch, MD
Phone: 303-315-1805
University of Colorado Hospital, Site Top medical professionals, superior medicine and progressive change make University...
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Aurora, CO
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Piedmont - Georgia Lung Associates
3820 Medical Park Drive Southwest
Austell, Georgia 30106
Principal Investigator: Chad Miller
Phone: 404-605-2986
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Austell, GA
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University of Maryland
Baltimore, Maryland 20742
(301) 405-1000
University of Maryland As a globally-connected university offering a world-class education, the University of Maryland...
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Baltimore, MD
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Sanatorio San José
Caba, Buenos Aires
Principal Investigator: Adrian Lescano, MD
Phone: 541148222748
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Caba,
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Indiana University Hospital
Carmel, Indiana 46032
Principal Investigator: William Harvey, MD
Phone: 317-435-8066
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Carmel, IN
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University of Cincinnati
2600 Clifton Ave
Cincinnati, Ohio 45267
(513) 556-6000
Principal Investigator: Jean Elwing, MD
Phone: 513-558-2148
University of Cincinnati The University of Cincinnati offers students a balance of educational excellence and...
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Cincinnati, OH
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University Hospital
Cleveland, Ohio 44106
Principal Investigator: Robert Schilz, DO, PhD
Phone: 216-844-2381
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Cleveland, OH
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Ohio State University
281 W. Lane Ave
Columbus, Ohio 43210
(614) 292-6446
Principal Investigator: Namita Sood, MD
Phone: 614-366-2761
Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
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Columbus, OH
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Henry Ford Health System
Detroit, Michigan 48202
Principal Investigator: Rana Awdish, M.D.
Phone: 313-916-1254
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Detroit, MI
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University of California San Francisco-Fresno
Fresno, California
Principal Investigator: Vijay Balasubramanian, MD
Phone: 559-459-4042
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Fresno, CA
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University of Iowa Hospitals and Clinics
200 Hawkins Dr,
Iowa City, Iowa 52242
866-452-8507
Principal Investigator: Linda Cadaret, MD
Phone: 319-353-7953
University of Iowa Hospitals and Clinics University of Iowa Hospitals and Clinics—recognized as one of...
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Iowa City, IA
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University of Florida College of Medicine Jacksonville- Division of Pulmonary & Critical Medicine
653 8th Street West
Jacksonville, Florida 32209
Principal Investigator: Abubakr Bajwa
Phone: 904-244-1106
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Jacksonville, FL
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Kentuckiana Pulmonary Associates
Louisville, Kentucky 40202
Principal Investigator: John McConnell, MD
Phone: 502-587-8000
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Louisville, KY
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Aurora Saint Lukes Medical Center
Milwaukee, Wisconsin 53215
Principal Investigator: Dianne Zwicke, MD
Phone: 414-649-5664
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Milwaukee, WI
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Newark Beth Israel Medical Center
201 Lyons Ave
Newark, New Jersey 07112
(973) 926-7000
Principal Investigator: Christina Migliore, MD
Phone: 973-926-8578
Newark Beth Israel Medical Center Newark Beth Israel Medical Center, a regional care, teaching hospital...
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Newark, NJ
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Sentara Cardiovascular Research Institute
Norfolk, Virginia 23507
Principal Investigator: Michael Eggert, MD
Phone: 757-388-4024
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Norfolk, VA
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Nebraska Medical Center
4242 Dewey Ave
Omaha, Nebraska 68105
(800) 922-0000
Principal Investigator: Austin Thompson, MD
Phone: 402-559-7585
Nebraska Medical Center Formed in 1997 by combining the operations of University Hospital, Bishop Clarkson...
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Omaha, NE
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HeartCare Midwest
Peoria, Illinois 61614
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Peoria, IL
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Perelman Center for Advanced Medicine at the University of Pennsylvania
Philadelphia, Pennsylvania 19104
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Philadelphia, PA
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Arizona Pulmonary Specialists, Ltd.
Phoenix, Arizona 85013
Principal Investigator: Jeremy Feldman, MD
Phone: 602-271-0832
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Phoenix, AZ
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University of Pittsburgh Medical Center - Presbyterian Cardiovascular Institute
Pittsburgh, Pennsylvania 15213
Principal Investigator: Michael Mathier, MD
Phone: 412-647-6000
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Pittsburgh, PA
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Legacy Research Institute
Portland, Oregon 97232
Principal Investigator: Catherine Markin, MD
Phone: 503-413-7945
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Portland, OR
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Virginia Commonwealth University
Richmond, Virginia 23298
(804) 828-0100
Principal Investigator: Daniel Grinnan
Virginia Commonwealth University Since our founding as a medical school in 1838, Virginia Commonwealth University...
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Richmond, VA
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David Geffen School of Medicine
Torrance, California 90502
Principal Investigator: Ronald Oudiz, MD
Phone: 310-222-3560
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Torrance, CA
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Beaumont Health
Troy, Michigan 48085
Principal Investigator: Samuel Allen, DO
Phone: 248-964-8524
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Troy, MI
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University of Arizona
Tucson, Arizona 85721
(520) 621-2211
University of Arizona The University of Arizona is a premier, public research university. Established in...
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