Detection of Immune Changes as a Result of Surgical Trauma in Human Subject
| Status: | Completed |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 10/19/2013 |
| Start Date: | March 2012 |
| End Date: | July 2013 |
| Contact: | Martin S Angst, MD |
| Email: | ang@stanford.edu |
| Phone: | 65-498-5109 |
Surgical trauma triggers a massive inflammatory response. Over time, both the innate and
adaptive branches of the immune system are affected by surgical trauma. The purpose of this
study to characterize the cellular and molecular mechanisms immune response to surgical
trauma. Additionally, detailed information about patients' recovery profile will be recorded
over a period of 6 weeks, with the eventual goal of linking immune responses to recovery
profiles.
Inclusion Criteria:
- 18 - 80
- Men and women
- Planning to undergo hip, knee or back surgery
Exclusion Criteria:
- Any systemic disease that might compromise the immune system (eg: lupus)
- Diagnosis of cancer
- Any condition that, in the opinion of the investigator, might compromise the
integrity of the study or safety of the participant.
- Unwilling to sign informed consent
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