A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Renal Impairment / Chronic Kidney Disease |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 8/31/2018 |
| Start Date: | March 27, 2013 |
| End Date: | January 10, 2020 |
Evaluation of the Benefits and Risks in Maintenance Renal Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based Immunosuppression
The primary purpose is to assess the benefits and risks of changing from Cyclosporine or
Tacrolimus to Belatacept between 6-60 months after kidney transplant.
Tacrolimus to Belatacept between 6-60 months after kidney transplant.
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com
Inclusion Criteria:
- Men and women, ages 18-75 inclusive
- Adult recipients of a renal allograft from a living donor or a deceased donor between
6-60 months prior to enrollment
- Receiving a stable (≥1 month) regimen of Calcineurin inhibitor (CNI) [Cyclosporine A
(CsA) or Tacrolimus (TAC)] with Mycophenolate mofetil (MMF) or Enteric Coated
Mycophenolate Sodium (EC-MPS)/Mycophenolic acid (MPA), and corticosteroids
- Stable renal function for 12 weeks prior to enrollment without new onset proteinuria
- Calculated glomerular filtration rate (cGFR) ≥30 and ≤75 mL/min/1.73 m2 [Modification
of Diet in Renal Disease study (MDRD) 4-formula]
Exclusion Criteria:
- Recipients with Epstein-Barr virus (EBV) serostatus negative or unknown
- History of acute rejection (AR) within 3 months prior to enrollment
- History of antibody mediated rejection
- Positive T-cell lymphocytotoxic cross match
- Proteinuria >1 g/day or >0.5 g/day if diabetic
We found this trial at
61
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Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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185 Cambridge Street
Boston, Massachusetts 02114
Boston, Massachusetts 02114
617-724-5200
Phone: 617-724-1270
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1211 Medical Center Dr
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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593 Eddy Street
Providence, Rhode Island 02903
Providence, Rhode Island 02903
401-444-4000
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Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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1120 15th Street
Augusta, Georgia 30909
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Chicago, Illinois 60612
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U.T. Southwestern Medical Center The story of UT Southwestern Medical Center is one of commitment...
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1400 8th Avenue
Fort Worth, Texas 76104
Fort Worth, Texas 76104
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2355 West Arlington Boulevard
Greenville, North Carolina 27834
Greenville, North Carolina 27834
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6411 Fannin Street
Houston, Texas 77030
Houston, Texas 77030
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2346 Mormon Trek Boulevard
Iowa City, Iowa 52240
Iowa City, Iowa 52240
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94 Old Short Hills Road
Livingston, New Jersey 07039
Livingston, New Jersey 07039
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Saint Barnabas Medical Center As a Barnabas Health facility, Saint Barnabas Medical Center is committed...
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Loma Linda, California 92354
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750 Highland Avenue
Madison, Wisconsin 53792
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1265 Union Avenue
Memphis, Tennessee 38104
Memphis, Tennessee 38104
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333 Cedar Street
New Haven, Connecticut 06511
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433 Bolivar Street
New Orleans, Louisiana 70112
New Orleans, Louisiana 70112
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600 Gresham Dr
Norfolk, Virginia 23507
Norfolk, Virginia 23507
(757) 388-3000
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Sentara Norfolk General Hospital Sentara Norfolk General Hospital is recognized as the number one ranked...
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2900 W Queen Ln
Philadelphia, Pennsylvania 19129
Philadelphia, Pennsylvania 19129
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Drexel University College of Medicine Drexel University College of Medicine represents the consolidation of two...
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University of Pittsburgh Medical Center UPMC is one of the leading nonprofit health systems in...
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Virginia Commonwealth University Medical Center The Virginia Commonwealth University Health System is an urban, comprehensive...
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Sacramento, California 95817
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2340 Clay Street
San Francisco, California 94115
San Francisco, California 94115
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1124 Columbia Street
Seattle, Washington 98122
Seattle, Washington 98122
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1959 Northeast Pacific Street
Seattle, Washington 98195
Seattle, Washington 98195
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101 W 8th Ave
Spokane, Washington 99204
Spokane, Washington 99204
(509) 474-3131
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Providence Sacred Heart Medical Center & Children's Hospital When Mother Joseph and the Sisters of...
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