ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients



Status:Terminated
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:10/14/2017
Start Date:June 2013
End Date:June 24, 2016

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Effects of Angiotensin Converting Enzyme Inhibitors on Total Hip and Knee Arthroplasty Patients

The purpose of this study is to determine the effects of Angiotension Converting Enzyme
Inhibitors (ACE-I) during surgery and in the immediate postoperative period for patients
undergoing elective total hip or knee arthroplasty.


Inclusion Criteria:

- Patients electing to undergo primary or revision total hip or knee arthroplasty

- Currently taking an ACE-I

Exclusion Criteria:

- Trauma patients

- Immunosuppressed patients (HIV/AIDS, organ transplant recipients, chemotherapy
patients, chronic steroid use)

- Patients with history of severe hypertension related illness such as hypertension
associated with stroke or myocardial infarction

- Patients in who continuation of their ACE-I is expressly mandated by their prescribing
physician
We found this trial at
1
site
Durham, North Carolina 27710
(919) 684-8111
Principal Investigator: Michael Bolognesi, MD
Duke University Younger than most other prestigious U.S. research universities, Duke University consistently ranks among...
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mi
from
Durham, NC
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