Ovarian Tissue Transplantation
| Status: | Recruiting |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 4/21/2016 |
| Start Date: | June 2013 |
| Contact: | Clarisa Gracia, MD |
| Email: | PennCancerTrials@emergingmed.com |
| Phone: | 877-204-9213 |
Autologous Orthotopic Transplantation of Previously Cryopreserved Ovarian Tissue
Chemotherapy and radiation therapy for the treatment of cancer can compromise fertility.
Ovarian tissue cryopreservation is an experimental strategy offered at The University of
Pennsylvania to preserve future fertility (protocol 806062). The primary objective of this
study is to determine the efficacy and safety of autologous transplantation of previously
cryopreserved ovarian cortical tissue in patients who experience infertility or ovarian
insufficiency after cancer treatments.
Ovarian tissue cryopreservation is an experimental strategy offered at The University of
Pennsylvania to preserve future fertility (protocol 806062). The primary objective of this
study is to determine the efficacy and safety of autologous transplantation of previously
cryopreserved ovarian cortical tissue in patients who experience infertility or ovarian
insufficiency after cancer treatments.
Inclusion Criteria:
- Female patient between the ages of 18 and 45 years
- Previously cryopreserved and stored cortical ovarian tissue available for autologous
transplantation
- Ovarian insufficiency defined as an elevated FSH over 10
- Inability to conceive after 6 months of unprotected intercourse with male
- Reasonably good health
- Candidate for pregnancy
- Written clearance for the procedure from the patients oncologist
Exclusion Criteria:
- Patients considered to be high risk for surgical complications will be excluded from
the research protocol
- Women who are known to be positive for the BRCA mutation
- Women with a history of leukemia, ovarian cancer or a cancer that likely involved the
ovaries at the time of ovarian tissue collection
- Women with psychological, psychiatric, or other conditions which prevent giving fully
informed consent
- Current pregnancy
We found this trial at
1
site
3400 Civic Center Blvd
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
(215) 662-6065
Principal Investigator: Clarisa Gracia, MD
Phone: 877-204-9213
Abramson Cancer Center of the University of Pennsylvania The Abramson Cancer Center of the University...
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