Nepafenac Once Daily for Macular Edema - Study 2

Inclusion Criteria:

- Planned cataract extraction by phacoemulsification with implantation of a posterior
chamber intraocular lens;

- History of Type 1 or 2 diabetes and non-proliferative diabetic retinopathy (NPDR)
(mild, moderate, or severe) in the study eye;

- Best-corrected visual acuity (BCVA) of 73 letters or worse in the study eye with
expectation of improvement after surgery;

- Understand and sign an informed consent document;

- Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

- Pre-existing macular edema in the study eye;

- History in the study eye of retinal detachment, wet age-related macular degeneration,
chronic or recurrent inflammatory eye disease, or prior procedures;

- Planned cataract surgery in the fellow eye prior to the Day 90 postoperative study
visit or through study exit;

- Planned multiple procedures for the study eye during the cataract/intraocular lens;

- Use of exclusionary medications, including nonsteroidal anti-inflammatory drugs
(NSAIDs) and steroids, as specified in protocol.

- Participation in any other clinical study within 30 days of the screening visit;

- Females of childbearing potential who are breast feeding, have a positive urine
pregnancy test at screening, are not willing to undergo a urine pregnancy test upon
entering or exiting the study, intend to become pregnant during the study, or do not
agree to use adequate birth control methods for the duration of the study;

- Other protocol-defined exclusion criteria may apply.