Efficacy and Safety of AIN457 (Secukinumab) in Patients With Relapsing Multiple Sclerosis

Inclusion Criteria:

- Diagnosis of Multiple Sclerosis according to 2010 revised McDonald criteria

- Disease duration of 10 years or less

- At least one relapse in the last year

- EDSS score 0 to 5.0 at entry

Exclusion Criteria:

- Active chronic disease of the immune system other than multiple sclerosis

- History of malignancy within the past 5 years

- Active systemic bacterial, viral or fungal infections

- Previous treatment with more than one class of multiple sclerosis therapies except
for previous treatment with glatiramer acetate and interferon-beta(s)

- Any medically unstable condition

- Unable to undergo MRI scans or repeated blood tests

- Pregnant or nursing females

- Women of child-bearing potential must use reliable forms of contraception

- Other protocol-defined inclusion/exclusion criteria may apply.