A Study of LY2605541 in Healthy Participants

Inclusion Criteria:

- Are overtly healthy males or females, as determined by medical history and physical
examination

- A body mass index of 18.5 to 30 kilograms per meter square (kg/m^2)

Exclusion Criteria:

- Have a history or presence of cardiovascular, respiratory, hepatic, renal,
gastrointestinal, endocrine, hematological, or neurological disorders capable of
significantly altering the absorption, metabolism, or elimination of drugs; of
constituting a risk when taking the study medication; or of interfering with the
interpretation of data

- Are women with a positive pregnancy test or are women who are lactating

- Intend to use over-the-counter medication within 7 days prior to dosing or
prescription medication within 14 days prior to dosing (apart from contraceptive
medication, vitamin/mineral supplements, occasional acetaminophen, and/or hormone
replacement therapy)

- Have donated blood of more than 500 milliliters (mL) within the last month

- Have an average weekly alcohol intake that exceeds 21 units per week (for males) and
14 units per week (for females)

- Are excessive consumers of xanthines (more than 10 cups of tea, coffee, cola, or hot
chocolate per day)

- Have a fasting blood glucose (BG) >110 milligrams per deciliter (mg/dL) (6.1
millimoles per liter [mmol/L])

- Currently smoke more than 10 cigarettes per day, or are unwilling to refrain from
smoking for 72 hours prior to each dosing occasion and during confinement